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Merck

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Sinonimi:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Specie:
ID UniProtKB:
ID gene:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Buspirone hydrochloride, ,
Specie
human
(R)-(+)-8-Hydroxy-DPAT hydrobromide, ≥98% (HPLC), solid,
Specie
human
Buspirone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Buspirone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Buspirone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
WAY-100635 maleate salt, powder,
Specie
human
1-(3-Methoxyphenyl)piperazine, 95%,
Specie
rat
GR 103691, ≥98% (HPLC), solid,
Specie
rat
1-(4-Methoxyphenyl)piperazine, 97%,
Specie
mouse, rat
Alverine citrate salt, ,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Serotonin antibody produced in rabbit, whole antiserum,
Reattività con
human, rat
Applicazione
immunohistochemistry
Anti-Serotonin Antibody, clone YC5/45, culture supernatant, clone YC5/45, Chemicon®,
Reattività con
human, lizard, mouse, pig, rabbit, rat
Applicazione
immunohistochemistry
Anti-Serotonin Receptor 1A Antibody, serum, Chemicon®,
Reattività con
rat
Applicazione
immunohistochemistry
Anti-5-HT-1A antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-HTR1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Trazodone hydrochloride, ≥99% (HPLC), powder,
Specie
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Specie
human
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human
Zimelidine dihydrochloride, solid,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Vilazodone hydrochloride, ≥98% (HPLC),
Specie
human
1,2,3,4-Tetrahydroisoquinoline, 95%,
Specie
rat, human
Trazodone hydrochloride, ≥99% (HPLC), powder,
Specie
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Specie
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Specie
human

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
BP897, >98% (HPLC), solid,
Specie
human, rat
Mifepristone, ≥98%,
Specie
human, mouse, rat
Haloperidol, powder,
Specie
human, rat
Clozapine, ,
Specie
human, rat

Small Molecule - Precursor

N° Catalogo
Descrizione
Specie
5-Hydroxy-L-tryptophan, powder,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human HTR1A,
Specie
human