This product is a rat monoclonal Antibody. An anti-rat secondary antibody would be suitable. Please see the link below to review examples of anti-rat secondary antibodies:
https://www.sigmaaldrich.com/US/en/search/anti-rat-antibody?facet=facet_product_category%3Asecondary%20antibodies&focus=products&page=1&perpage=30&sort=relevance&term=anti-rat%20antibody&type=product
MAB352
Anti-Serotonin Antibody, clone YC5/45
culture supernatant, clone YC5/45, Chemicon®
Sinonimo/i:
5-HT
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100 μL
CHF 297.00
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Cambia visualizzazione
100 μL
CHF 297.00
About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
rat
Livello qualitativo
Forma dell’anticorpo
culture supernatant
Tipo di anticorpo
primary antibodies
Clone
YC5/45, monoclonal
Reattività contro le specie
mouse, human, rat, lizard, rabbit, pig
Produttore/marchio commerciale
Chemicon®
tecniche
immunohistochemistry: suitable
Isotipo
IgG
Condizioni di spedizione
dry ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... HTR1A(3350)
Specificità
Recognizes the formaldehyde conjugate of serotonin. Without paraformaldehyde treatment, it cross-reacts in liquid phase with dopamine and tryptamine in hemagglutination tests. Shows no reactivity with catecholamine-containing neurons in formaldehyde fixed preparations. MAB352 reacts with serotonin in neurons and recognizes serotonergic sites in fixed tissue sections. By cell agglutination, no cross reactivity with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin.
Immunogeno
Serotonin conjugated to BSA.
Applicazioni
Anti-Serotonin Antibody, clone YC5/45 is an antibody against Serotonin for use in IH.
Immunohistochemistry at 1:100-1:200 for formaldehyde fixed tissue.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Stato fisico
Lyophilized Supernatant, preservative free.
Unpurified
Stoccaggio e stabilità
Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze-thaw cycles.
Risultati analitici
Control
Brain tissue
Brain tissue
Altre note
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Anna Casanovas et al.
Scientific reports, 7, 40155-40155 (2017-01-10)
The electric activity of lower motor neurons (MNs) appears to play a role in determining cell-vulnerability in MN diseases. MN excitability is modulated by cholinergic inputs through C-type synaptic boutons, which display an endoplasmic reticulum-related subsurface cistern (SSC) adjacent to
Tanimul Alam et al.
Nature communications, 7, 10388-10388 (2016-01-23)
The molecular mechanisms underlying the ability of axons to regenerate after injury remain poorly understood. Here we show that in Caenorhabditis elegans, axotomy induces ectopic expression of serotonin (5-HT) in axotomized non-serotonergic neurons via HIF-1, a hypoxia-inducible transcription factor, and
Alexander Drobyshevsky et al.
Journal of neurochemistry, 132(4), 394-402 (2014-11-26)
We hypothesized that a deficiency in the descending serotonergic input to spinal cord may underlie postnatal muscle hypertonia after global antenatal hypoxic-ischemic injury in a rabbit model of cerebral palsy. Neurotransmitter content was determined by HPLC in the spinal cord
Presenilin1 regulates histamine neuron development and behavior in zebrafish, danio rerio.
Sundvik, M; Chen, YC; Panula, P
The Journal of Neuroscience null
Basudha Basu et al.
Reproduction (Cambridge, England), 135(5), 657-669 (2008-02-29)
Serotonin is reported to be present in early embryos of many species and plays an important role in early patterning. Since it is a fluorophore, it can be directly visualized using fluorescence microscopy. Here, we use three-photon microscopy to image
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MAB352 Is this a mouse monoclonal Ab? I see Rat in the source which is unusual for me. What secondary is ideal
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