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Merck

1444279

USP

Mirtazapin

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

(±)-1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin

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350 MG
CHF 2’010.00

CHF 2’010.00


Voraussichtliches Versanddatum29. Mai 2025


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350 MG
CHF 2’010.00

About This Item

Empirische Formel (Hill-System):
C17H19N3
CAS-Nummer:
Molekulargewicht:
265.35
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

CHF 2’010.00


Voraussichtliches Versanddatum29. Mai 2025


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Qualität

pharmaceutical primary standard

API-Familie

mirtazapine

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

CN1CCN2C(C1)c3ccccc3Cc4cccnc24

InChI

1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3

InChIKey

RONZAEMNMFQXRA-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Mirtazapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Mirtazapine Tablets
  • Mirtazapine Orally Disintegrating Tablets
  • Mirtazapine Compounded Oral Suspension, Veterinary

Biochem./physiol. Wirkung

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Mirtazapine Compounded Oral Suspension, Veterinary
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(5), 2977-2977 (2019)
Mirtazapine
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(6), 2976-2976 (2021)
Mirtazapine Orally Disintegrating Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(2), 2980-2980 (2020)
Hun Soo Chang et al.
Journal of neural transmission (Vienna, Austria : 1996), 122(1), 59-68 (2014-12-03)
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis is among the most consistent neuroendocrine abnormalities in major depressive disorder (MDD). The peptide adrenocorticotropin hormone (ACTH) mediates HPA axis function during stress and is encoded by the proopiomelanocortin (POMC) gene polycistronically. After screening
Hun Soo Chang et al.
Journal of clinical psychopharmacology, 34(4), 446-454 (2014-06-10)
We tested for the association of HTR1A and 5-HTT genetic polymorphisms with treatment response to mirtazapine and evaluated the interactive effect between the polymorphisms in 283 patients with major depressive disorder. Korean subjects with diagnosis of major depressive disorder using

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