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Merck

1125006

USP

Chlorpromazin -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

2-Chlor-10-(3-dimethylaminopropyl)-phenothiazin -hydrochlorid, CPZ, Largactil

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About This Item

Empirische Formel (Hill-System):
C17H19ClN2S · HCl
CAS-Nummer:
Molekulargewicht:
355.33
Beilstein:
3779989
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

chlorpromazine

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChIKey

FBSMERQALIEGJT-UHFFFAOYSA-N

Angaben zum Gen

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Chlorpromazine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Chlorpromazine
  • Chlorpromazine Hydrochloride
  • Chlorpromazine Hydrochloride Injection
  • Chlorpromazine Hydrochloride Oral Concentrate
  • Chlorpromazine Hydrochloride Syrup
  • Chlorpromazine Hydrochloride Tablets
Ersatz für Benzidin, o-Dianisid und o-Tolidin bei der Bestimmung von Mikromengen von Hämoglobin und Peroxidase.

Biochem./physiol. Wirkung

Chlorpromazin zeigt zytotoxische und antiproliferative Aktivität gegen Leukämiezellen, beeinträchtigt jedoch die Lebensfähigkeit normaler Lymphozyten nicht.
Phenothiazin antipsychotisch; D2 Dopamin-Rezeptor-Antagonist, H1 Histamin-Rezeptor-Antagonist; hemmt Calmodulin-abhängige Stimulation zyklischer Nucleotid-Phosphodiesterase und der Stickstoffoxidsynthase.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Skull and crossbones

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Outbreaks of emerging infections present health professionals with the unique challenge of trying to select appropriate pharmacologic treatments in the clinic with little time available for drug testing and development. Typically, clinicians are left with general supportive care and often

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