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T4626

Sigma-Aldrich

Nα-p-Tosyl-L-arginin-methylester -hydrochlorid

≥98% (TLC), suitable for ligand binding assays

Synonym(e):

TAME

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About This Item

Lineare Formel:
H2NC(=NH)NH(CH2)3CH(NHSO2C6H4CH3)CO2CH3 · HCl
CAS-Nummer:
1784-03-8
Molekulargewicht:
378.87
Beilstein:
3922357
EG-Nummer:
217-235-1
MDL-Nummer:
MFCD00012578
UNSPSC-Code:
12352103
eCl@ss:
32160406
PubChem Substanz-ID:
24900058
NACRES:
NA.26

product name

Nα-p-Tosyl-L-arginin-methylester -hydrochlorid,

Assay

≥98% (TLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

white

mp (Schmelzpunkt)

145-147 (lit.)

Lagertemp.

−20°C

SMILES String

Cl.COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1

InChIKey

JIQFFACVQXXHMY-YDALLXLXSA-N

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Anwendung

Nα-p-Tosyl-L-arginine methyl ester hydrochloride has been used as an esterolytic substrate to assess trypsin-like activity in midgut extracts. It has also been used as a substrate for measuring trypsin activity of pancreatin and human intestinal samples.

Biochem./physiol. Wirkung

Nα-p-Tosyl-L-arginine methyl ester (TAME) binds to anaphase-promoting complex (APC) and prevents its activation by Cdc20 and Cdh1.

Substrate

Substrate for trypsin, thrombin, plasmin, and other proteases.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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