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SRP8033

Sigma-Aldrich

IL-1β mouse

recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)

Synonym(e):

Interleukin-1beta, Postn

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.32

Biologische Quelle

mouse

Rekombinant

expressed in E. coli

Konjugat

untagged

Assay

>95% (SDS-PAGE)

Form

lyophilized

Mol-Gew.

~17 kDa by SDS-PAGE

Verpackung

pkg of 10 μg

Lagerbedingungen

avoid repeated freeze/thaw cycles

Methode(n)

immunohistochemistry: suitable

Verunreinigungen

<0.1 EU/μg endotoxin, tested

Farbe

white

UniProt-Hinterlegungsnummer

P10749

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

mouse ... Il1b(16176)

Allgemeine Beschreibung

Interleukin-1β (IL-1β) is produced by activated macrophages. It belongs to the IL-1 family of proteins that are involved in the inflammatory response.

Biochem./physiol. Wirkung

Interleukin-1β (IL-1β) stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation and fibroblast growth factor activity. IL-1β, in most situations requires the inflammasome complex to be cleaved and secreted. This protein may modulate the effects of eosinophils in the intestine.

Physikalische Form

Lyophilized from PBS.

Rekonstituierung

Reconstitute with 100 μL deionized water.

Sonstige Hinweise

Mouse IL-1beta (aa 118-269) is untagged.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

IL-1? in eosinophil-mediated small intestinal homeostasis and IgA production.
Jung Y
Mucosal Immunology, 8(4), 930-942 (2015)
Understanding the mechanism of IL-1? secretion.
Lopez-Castejon G and Brough D
Cytokine & Growth Factor Reviews, 22(4), 189-195 (2011)
Ruojia Ma et al.
Drug development research, 83(3), 735-744 (2021-12-21)
Type 2 diabetes mellitus (T2DM) is a metabolic risk factor associated with non-alcoholic liver disease (NAFLD). Schisandrin B (Sch B) is a promising agent for NAFLD. However, the actions of Sch B on diabetes-associated NAFLD and the underlying mechanisms are
Dongmin Xu et al.
Experimental and therapeutic medicine, 23(1), 14-14 (2021-11-25)
Perfluorooctane sulfonate (PFOS) is a persistent pollutant that exerts toxicity and induces cardiogenesis in humans and animals. Yet, the effect of PFOS exposure on cardiac toxicity in adult rats has, to our knowledge, not been reported and the mechanism still
Hai-Lei Guo et al.
Inflammation, 44(1), 358-370 (2020-10-13)
The inflammatory response involving interleukin-1β (IL-1β) has been thought to play an important role in the development of late-phase sepsis. However, in this study, we wanted to explore the possibility of using IL-1β to improve the prognosis of sepsis by
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