SML1266

Bryostatin 2

≥95% (HPLC)

• Synonym(e): (+)-Bryostatin 2, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-Tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-
• Empirische Formel (Hill-System): C₄₅H₆₆O₁₆
• CAS-Nummer: 87745-28-6
• Molekulargewicht: 863.00
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: Bugula neritina (sponge)
• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: film
• Farbe: colorless to light yellow
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• InChI: 1S/C45H66O16/c1-9-10-11-12-13-14-37(49)59-41-29(21-39(51)56-8)20-32-24-35(27(2)46)58-40(52)23-30(47)22-33-25-36(48)43(5,6)44(53,60-33)26-34-18-28(19-38(50)55-7)17-31(57-34)15-16-42(3,4)45(41,54)61-32/h11-16,19,21,27,30-36,41,46-48,53-54H,9-10,17-18,20,22-26H2,1-8H3/b12-11+,14-13+,16-15+,28-19-,29-21+/t27-,30-,31?,32?,33-,34+,35-,36+,41+,44+,45-/m1/s1
• InChIKey: LIPGUSBNMQRYNL-WZYRAJGLSA-N

Beschreibung

Biochem./physiol. Wirkung

Bryostatin 2 is potent protein kinase C activator (Ki = 5.9 nM) and an antagonist to phorbol ester tumor promoter 12-0-tetradecanoylphorbol-13-acetate (TPA). Bryostatin 2 exhibits antineoplastic activity against the murine P388 lymphocytic leukemia and human U937 cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable