P4279

L-α-Phosphatidylcholin

egg yolk, Type XIII-E, 100 mg/mL in ethanol, solution

• Synonym(e): 1,2-Diacyl-sn-glycero-3-phosphocholin, 3-sn-Phosphatidylcholin, L-α-Lecithin, Azolectin, PC
• CAS-Nummer: 8002-43-5
• Beilstein: 5209585
• UNSPSC-Code: 51321705
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: egg yolk
• Typ: Type XIII-E
• Assay: ≥99% (TLC)
• Form: solution
• Konzentration: 100 mg/mL in ethanol
• Funktionelle Gruppe: phospholipid
• Lipid-Typ: phosphoglycerides
• Lagertemp.: −20°C
• SMILES String: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
• InChIKey: JLPULHDHAOZNQI-ZTIMHPMXSA-N

Beschreibung

Allgemeine Beschreibung

Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells.[1] This structural component of the cellular membrane is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet-activating factor, and arachidonic acid.

Anwendung

L-α-Phosphatidylcholine has been used in differential lipid partitioning experiments of xenobiotics and natural compounds to determine trioleoylglycerol (TG) and phosphatidylcholine (PC) coefficients (KTG/PC) for partitioning of lipophilic chemicals.[2]

Biochem./physiol. Wirkung

Ein großes strukturelles Phospholipid im Gehirn, das schätzungsweise 15 % der Gesamtlipide enthält; befindet sich hauptsächlich in der grauen Substanz.

Phosphatidylcholine serves as a reservoir for several lipid messengers.[1] Phosphatidylcholine is used for the preparation of vesicle suspensions, commonly called liposomes or monolayers.[3]

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H319
• P-Sätze: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 60.8 °F
• Flammpunkt (°C): 16 °C
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter