P3921
Parathyroid Hormone Fragment 1-34 rat
≥97% (HPLC), powder
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About This Item
Empirische Formel (Hill-System):
C180H291N55O48S2
CAS-Nummer:
Molekulargewicht:
4057.71
MDL-Nummer:
UNSPSC-Code:
51111800
NACRES:
NA.32
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Qualitätsniveau
Assay
≥97% (HPLC)
Form
powder
UniProt-Hinterlegungsnummer
Lagertemp.
−20°C
Angaben zum Gen
rat ... Pth(24694)
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Amino Acid Sequence
Ala-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-leu-Ala-Ser-Val-Glu-Arg-Met-Gln-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe
Anwendung
Parathyroid Hormone Fragment 1-34 rat has been used to study the in vivo effect of parathyroid hormone (PTH) on the intestinal HCO3-secretion in rats. It has also been injected into rats to increase PTH levels and study its effect on the high-phosphate diet-induced elevation of blood pressure.
Biochem./physiol. Wirkung
Parathyroid Hormone Fragment 1-34 is a parathyroid hormone (PTH) analog. It is implicated in the stimulation of intracellular cAMP accumulation and it induces osteocalcin (OC) promoter activity.
Sonstige Hinweise
Lyophilized from 0.1% TFA in H2O
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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X P Yu et al.
Endocrinology, 138(8), 3085-3092 (1997-08-01)
Osteocalcin (OC) is a bone-specific extracellular matrix protein expressed by mature osteoblasts during late stages of differentiation. Previous studies have shown that forskolin, an activator of adenylate cyclase, stimulated OC production. Because PTH has been shown to activate several intracellular
Narattaphol Charoenphandhu et al.
Biochemical and biophysical research communications, 409(4), 775-779 (2011-05-31)
Parathyroid hormone (PTH) was recently demonstrated to enhance the HCO(3)(-) secretion through the apical anion channel, cystic fibrosis transmembrane conductance regulator (CFTR), but how the HCO(3)(-) entered the epithelial cells was not well understood, in part, due to the lack
Milica Bozic et al.
Journal of hypertension, 32(9), 1822-1832 (2014-07-01)
There is growing evidence suggesting that phosphate intake is associated with blood pressure levels. However, data from epidemiological studies show inconsistent results. The present study was designed to evaluate the effect of high circulating phosphorus on arterial blood pressure of
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