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O2750
Orotsäure
Orotic acid
≥98% (titration), anhydrous
Synonym(e):
2,6-Dihydroxy-pyrimidin-4-carbonsäure, 6-Carboxy-uracil, Uracil-6-carbonsäure
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10 G
CHF 60.60
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10 G
CHF 60.60
About This Item
Empirische Formel (Hill-System):
C5H4N2O4
CAS-Nummer:
Molekulargewicht:
156.10
Beilstein:
383901
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.51
Empfohlene Produkte
Qualität
anhydrous
Qualitätsniveau
Assay
≥98% (titration)
mp (Schmelzpunkt)
≥300 °C
SMILES String
OC(=O)C1=CC(=O)NC(=O)N1
InChI
1S/C5H4N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)
InChIKey
PXQPEWDEAKTCGB-UHFFFAOYSA-N
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Anwendung
Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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