N8130

4-Nitrophenylacetat

esterase substrate, chromogenic, ≥98% (TLC), powder or crystals

• Synonym(e): 4-Nitrophenyl-acetat
• Lineare Formel: CH₃CO₂C₆H₄NO₂
• CAS-Nummer: 830-03-5
• Molekulargewicht: 181.15
• Beilstein: 515874
• EG-Nummer: 212-593-5
• MDL-Nummer: MFCD00007326
• UNSPSC-Code: 12352204
• PubChem Substanz-ID: 24897853
• NACRES: NA.32

Eigenschaften

• Produktbezeichnung: 4-Nitrophenylacetat, esterase substrate
• Qualitätsniveau: 200
• Assay: ≥98% (TLC)
• Form: powder or crystals
• mp (Schmelzpunkt): 75-77 °C (lit.)
• Lagertemp.: −20°C
• SMILES String: CC(=O)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
• InChIKey: QAUUDNIGJSLPSX-UHFFFAOYSA-N
• Angaben zum Gen: human ... PON1(5444)

Beschreibung

Anwendung

4-Nitrophenyl acetate has been used:

• to evaluate esterase activity in human embryonic kidney cell line[1]
• in carbonic anhydrase inhibition assay[2]
• to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin[3]
• as a substrate to determine carboxylesterase (CES) activity in mouse liver cells[4][5]
• to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix[6]

Substrate

Chromogenic esterase substrate.

Sicherheitshinweise

• Piktogramme: GHS03,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H272,H317,H318
• P-Sätze: P210 - P220 - P261 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
• Lagerklassenschlüssel: 5.1B - Oxidizing hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)