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F3627

Sigma-Aldrich

D-Fructose 6-phosphat Dinatriumsalz Hydrat

≥98%, amorphous powder

Synonym(e):

Sodium (2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl phosphate

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About This Item

Empirische Formel (Hill-System):
C6H11Na2O9P · xH2O
CAS-Nummer:
26177-86-6
Molekulargewicht:
304.10 (anhydrous basis)
Beilstein:
5686786
MDL-Nummer:
MFCD16661244
UNSPSC-Code:
12352201
PubChem Substanz-ID:
329799699
NACRES:
NA.25
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Biologische Quelle

bacterial (Corynebacterium)

Qualitätsniveau

300

Assay

≥98%

Form

amorphous powder

Verunreinigungen

<0.05 mol % fructose 1,6-diphosphate
<1.5 mol % glucose 6-phosphate

Farbe

white to off-white

Löslichkeit

H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

Kationenspuren

Na: 14.6-15.6% (dry basis)

Anwendung(en)

agriculture

Lagertemp.

−20°C

SMILES String

O.[Na+].[Na+].OC[C@@]1(O)O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-2-6(10)5(9)4(8)3(15-6)1-14-16(11,12)13;;;/h3-5,7-10H,1-2H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t3-,4-,5+,6-;;;/m1.../s1

InChIKey

VSCMQICEHMPOEC-HTKRKRNRSA-L

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Verwandte Kategorien

Anwendung

D-Fructose-6-phosphat (F6P) ist ein Zuckerzwischenprodukt des glykolytischen Signalwegs, das zur Identifizierung, Differenzierung und Charakterisierung von Enzymen wie Phosphofructokinase(n), pyrophosphatabhängigen Fructose-6-phosphat-1-phosphotransferase(n), D-Fructose-6-phosphat-Aldolase(n), Glutamin:Fructose-6-phosphat-Amidotransferase(n) und Glucosamin-6P-Synthase(n) verwendet werden kann.

Biochem./physiol. Wirkung

Fructose-6-phosphat ist ein glykolytisches Zwischenprodukt, das durch die Isomerisierung von Glucose-6-phosphat mittels Phosphoglucoisomerase erzeugt wird.

Sonstige Hinweise

Für einen umfassenden Überblick über unser vielfältiges Angebot an Monosacchariden für Ihre Forschung empfehlen wir Ihnen den Besuch unserer Seite zur Kategorie Kohlenhydrate.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H315,H319

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000434826
0000434829
0000434828
0000434827
0000434827

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Die Dokumentenbibliothek aufrufen

Yimin Qian et al.
Bioorganic & medicinal chemistry letters, 21(21), 6264-6269 (2011-10-01)
Through high throughput screening and subsequent hit identification and optimization, we synthesized a series of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as the first reported potent and reversible GFAT inhibitors. SAR studies of this class of compounds indicated significant impact on GFAT inhibition potency
Kay O Broschat et al.
The Journal of biological chemistry, 277(17), 14764-14770 (2002-02-14)
Glutamine-fructose-6-phosphate amidotransferase (GFAT) catalyzes the first committed step in the pathway for biosynthesis of hexosamines in mammals. A member of the N-terminal nucleophile class of amidotransferases, GFAT transfers the amino group from the L-glutamine amide to D-fructose 6-phosphate, producing glutamic
Quan Wang et al.
Glycobiology, 22(12), 1760-1767 (2012-07-27)
Streptococcus pneumoniae is a major human pathogen associated with diseases worldwide. The capsular polysaccharides (CPSs) are considered a major virulence factor and are targets for a vaccine. d-Mannitol was found to be present in the CPS of several S. pneumoniae
Minsuh Seo et al.
PloS one, 6(9), e24179-e24179 (2011-10-01)
Cancer cells adopt glycolysis as the major source of metabolic energy production for fast cell growth. The HIF-1-induced PFKFB3 plays a key role in this adaptation by elevating the concentration of Fru-2,6-BP, the most potent glycolysis stimulator. As this metabolic
María Cruz Rodríguez et al.
PloS one, 7(12), e50876-e50876 (2012-12-29)
Bacteria of the genus Brucella have the unusual capability to catabolize erythritol and this property has been associated with their virulence mainly because of the presence of erythritol in bovine foetal tissues and because the attenuated S19 vaccine strain is
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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