B1682

BAD from mouse

≥70% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

• MDL-Nummer: MFCD03456151
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Rekombinant: expressed in E. coli
• Qualitätsniveau: 200
• Beschreibung: full-length murine Bad with an N-terminal histidine-tag.
• Assay: ≥70% (SDS-PAGE)
• Form: buffered aqueous glycerol solution
• Mol-Gew.: 31 kDa
• UniProt-Hinterlegungsnummer: Q61337
• Lagertemp.: −20°C
• Angaben zum Gen: mouse ... Bad(12015)

Beschreibung

Biochem./physiol. Wirkung

Bad, a pro-apoptotic factor, is a member of the Bcl-2 family. Cytokine-induced phosphorylation of Bad results in it being sequested in the cytosol. In the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.

Physikalische Form

Supplied as a solution in phosphate buffered saline containing 250 mM imidizole and 50% glycerol.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H315,H319,H360D
• P-Sätze: P201 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable