A8264

4-Aminophthalhydrazid

≥98% (HPLC), powder

• Synonym(e): 6-Amino-2,3-dihydro-1,4-phthalazindion, Isoluminol
• Empirische Formel (Hill-System): C₈H₇N₃O₂
• CAS-Nummer: 3682-14-2
• Molekulargewicht: 177.16
• Beilstein: 164804
• MDL-Nummer: MFCD00010560
• UNSPSC-Code: 12352204
• PubChem Substanz-ID: 24891326
• NACRES: NA.83

Eigenschaften

• Produktbezeichnung: 4-Aminophthalhydrazid,
• Assay: ≥98% (HPLC)
• Qualitätsniveau: 200
• Form: powder
• mp (Schmelzpunkt): 300 °C (lit.)
• Löslichkeit: 2 M NH₄OH: 50 mg/mL, clear to slightly hazy
• SMILES String: Nc1ccc2C(=O)NNC(=O)c2c1
• InChI: 1S/C8H7N3O2/c9-4-1-2-5-6(3-4)8(13)11-10-7(5)12/h1-3H,9H2,(H,10,12)(H,11,13)
• InChIKey: HUDPLKWXRLNSPC-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Aminophthalhydrazide has been used in:

• chemiluminescence-based reactive oxygen species (ROS) assay in bone marrow (BM) neutrophils post-Yersinia pseudotuberculosis infection
• neutrophil ROS assays post-K. pneumonia exposure
• neutrophil ROS assays in response to formylated-methionine-leucine-proline

Biochem./physiol. Wirkung

4-Aminophthalhydrazide or isoluminol is a chemiluminescent compound that comprises a phthalazine ring. It is more hydrophilic than luminol. Isoluminol is commercially used in a wide variety of in vitro immunoassays and is a chemiluminescence amplifier for studying reactive oxygen species. It is also useful as an electroluminescence (ECL) biosensor and as a probe for rapid microbial detection.

Leistungsmerkmale und Vorteile

Produces chemiluminescence.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves