A4685

Luminol Natriumsalz

luminescent, ≥98% (titration), powder and chunks

• Synonym(e): 3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione
• Lineare Formel: C₈H₆N₃O₂Na
• CAS-Nummer: 20666-12-0
• Molekulargewicht: 199.14
• UNSPSC Code: 12352204
• PubChem Substance ID: 24890898
• NACRES: NA.83
• MDL number: MFCD00161491

Eigenschaften

• Produktname: Luminol Natriumsalz,
• assay: ≥98% (titration)
• Quality Segment: 300
• form: powder and chunks
• solubility: water: 50 mg/mL, clear to very slightly hazy, colorless to faint red
• SMILES string: O=C1NN([Na])C(C2=CC=CC(N)=C21)=O
• InChI: 1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,(H4,9,10,11,12,13);/q;+1/p-1
• InChI key: RVJVDCVIJCBUTH-UHFFFAOYSA-M

Beschreibung

Application

Luminol sodium salt has been used:

• as a component of MEBSS buffer in a bioluminescence assay to detect peroxidase activity in whole blood samples[1]
• to study protein interaction in whole-cell lysates by immunoprecipitation[2]
• for in vitro reactive oxygen species (ROS) quantification in CD45⁺ and CD45− cells

Biochem/physiol Actions

Luminol is a redox-sensitive chemiluminescent compound.[3] It emits blue luminescence when the basic aqueous solution of luminol having oxygen atoms come in contact with oxidizing agents like potassium ferricyanide. It is highly stable and is applicable in various fields such as analytical chemistry, metallurgy, biochemistry, and forensics for detecting reactive species.[3] Luminol has the potential to detect defects in neutrophils ex vivo during oxidative metabolism defects such as chronic granulomatous disease and myeloperoxidase deficiency.[3]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves