95140

Retinylacetat

concentrate (~50% (w/w) in peanut oil), ~1500 U/mg

• Synonym(e): Retinolacetat, Vitamin A-acetat
• Empirische Formel (Hill-System): C₂₂H₃₂O₂
• CAS-Nummer: 127-47-9
• Molekulargewicht: 328.49
• Beilstein: 1915439
• MDL-Nummer: MFCD00019413
• UNSPSC-Code: 12352200
• eCl@ss: 34058009
• PubChem Substanz-ID: 57653653
• NACRES: NA.79

Eigenschaften

• Biologische Quelle: synthetic
• Assay: ~95% (HPLC)
• Form: liquid
• Qualität: concentrate (~50% (w/w) in peanut oil)
• Spezifische Aktivität: ~1500 U/mg
• Enthält: DL-α-tocopherol as stabilizer
• Farbe: yellow to very dark yellow
• mp (Schmelzpunkt): 57-58 °C
• Lagertemp.: 2-8°C
• SMILES String: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• InChIKey: QGNJRVVDBSJHIZ-QHLGVNSISA-N

Beschreibung

Allgemeine Beschreibung

Vitamin A is also known as retinol. Retinaldehyde, retinoic acid and retinyl esters are the derivatives of retinol. Retinol consists of a 20-carbon molecule. It also contains a cyclohexanyl ring with a side chain of four double bonds and an alcohol end group. Vitamin A is naturally present in the body as retinyl ester and β-carotene. Retinyl acetate, retinyl propionate and retinyl palmitate are analogs of retinol.

Biochem./physiol. Wirkung

Retinyl esters are stored in the liver and get converted to retinol before absorption by the intestine. Retinal plays a role in eye vision as it is a part of rhodopsin. Retinol binds to the retinol binding proteins in the plasma. Retinyl acetate has applications in cosmetology.

Sonstige Hinweise

Isomerenreinheit: ~95% all-trans- und ~5% 13- cis-Isomer

Review: Systematic mode of action of vitamin A

Vorsicht

kristallisiertes Produkt kann durch Erhitzen auf 65°C wieder verflüssigt werden

Einheitendefinition

1 U entspricht 1 Internationalen Einheit gemäss Ph Eur II, 217 (1983)

Physikalische Form

kann teilweise kristallisieren

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360D,H413
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Aquatic Chronic 4 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter