04632

N-Methyl-L-tyrosin

≥98% (HPLC)

• Synonym(e): (S)-3-(4-Hydroxyphenyl)-2-(methylamino)-propionsäure, N-Me-Tyr-OH, Surinamin
• Empirische Formel (Hill-System): C₁₀H₁₃NO₃
• CAS-Nummer: 537-49-5
• Molekulargewicht: 195.22
• Beilstein: 2646795
• EG-Nummer: 208-670-8
• MDL-Nummer: MFCD00238322
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 329747962

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder or crystals
• Optische Aktivität: [α]/D +16.0±1.0°, c = 1 in 1 M HCl
• Zusammensetzung: carbon, 60.7-62.3% ; nitrogen, 6.9-7.5%
• Farbe: colorless to white
• Anwendung(en): cell analysis
• SMILES String: CN[C@@H](Cc1ccc(O)cc1)C(O)=O
• InChI: 1S/C10H13NO3/c1-11-9(10(13)14)6-7-2-4-8(12)5-3-7/h2-5,9,11-12H,6H2,1H3,(H,13,14)/t9-/m0/s1
• InChIKey: AXDLCFOOGCNDST-VIFPVBQESA-N

Beschreibung

Anwendung

N-Methyl-L-tyrosine was used in experiments as a control group to show that methylation of the imino group in N-p-phenylpropionyl-L-tyrosine eliminates its inhibitory effect on the firing of the giant neurone of the giant African snail.

Biochem./physiol. Wirkung

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319
• P-Sätze: P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable