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Y0001460

Acetylsalicylsäure für die Peakidentifizierung

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

Acetylsalicylsäure, 2-Acetoxybenzoesäure, ASA, Aspirin

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About This Item

Lineare Formel:
2-(CH3CO2)C6H4CO2H
CAS-Nummer:
Molekulargewicht:
180.16
Beilstein:
779271
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

aspirin

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

134-136 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

CC(=O)Oc1ccccc1C(O)=O

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

InChIKey

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Angaben zum Gen

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Acetylsalicylic acid for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Verhindert durch Hemmung der Cyclooxygenase (Prostaglandin H Synthase) die Produktion von Prostaglandinen mit höher Selektivität für COX-1. Für den antithrombotischen Effekt ist die Hemmung von COX-1 in Thrombozyten verantwortlich, welches die Produktion von Thromboxan und die Blutplättchenaggregation hemmt. Chemopräventive Wirkung gegenüber kolorektalen und anderen soliden Tumoren.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

482.0 °F

Flammpunkt (°C)

250 °C


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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Gideon Sahar et al.
The Journal of thoracic and cardiovascular surgery, 149(4), 1042-1050 (2015-04-25)
We compared the flow rates, reactivity, and morphology of the distal internal thoracic artery and its branches, the superior epigastric and musculophrenic arteries, to test their applicability as possible conduits in coronary artery bypass grafting surgeries. Skeletonized internal thoracic artery
Yu-Chi Tung et al.
Medical care, 52(6), 519-527 (2014-05-03)
A volume-outcome relationship has been found for acute myocardial infarction (AMI); however, the mechanisms underlying the relationship remain unclear. In particular, it is not known whether processes of care are mediators of the volume-outcome relationship, that is, whether the mechanisms
Gwen M C Masclee et al.
Gastroenterology, 147(4), 784-792 (2014-06-18)
Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs) and low-dose aspirin increases the risk of upper gastrointestinal bleeding (UGIB). Guidelines suggest avoiding certain drug combinations, yet little is known about the magnitude of their interactions. We estimated the risk of UGIB
T N Bonten et al.
Thrombosis and haemostasis, 112(6), 1209-1218 (2014-09-12)
The risk of acute cardiovascular events is highest during morning hours, and platelet activity peaks during morning hours. The effect of timing of aspirin intake on circadian rhythm and morning peak of platelet reactivity is not known. It was our
Ahmed Kayssi et al.
Journal of vascular surgery, 60(1), 106-110 (2014-03-25)
Acute limb ischemia (ALI) in pediatric patients is rare but may lead to limb loss and life-long complications. This study reviewed the experience of a Canadian tertiary pediatric center with the medical and operative management of ALI. The medical records of

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