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O5380

Supelco

Oxethazain

analytical standard

Synonym(e):

2-Hydroxyethylimino-bis-[N-(α,α-dimethylphenethyl)-N-methylacetamid], Oxetacain

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5 G
CHF 143.00

CHF 143.00

Voraussichtliches Versanddatum28. Mai 2025

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5 G
CHF 143.00

About This Item

Empirische Formel (Hill-System):
C28H41N3O3
CAS-Nummer:
126-27-2
Molekulargewicht:
467.64
EG-Nummer:
204-780-5
MDL-Nummer:
MFCD00079202
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329818914
NACRES:
NA.24

CHF 143.00

Voraussichtliches Versanddatum28. Mai 2025

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Qualität

analytical standard

Qualitätsniveau

200

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2

InChI

1S/C28H41N3O3/c1-27(2,19-23-13-9-7-10-14-23)29(5)25(33)21-31(17-18-32)22-26(34)30(6)28(3,4)20-24-15-11-8-12-16-24/h7-16,32H,17-22H2,1-6H3

InChIKey

FTLDJPRFCGDUFH-UHFFFAOYSA-N

Allgemeine Beschreibung

Oxethazaine is a topical anesthetic, administered as an antacid for treating pain associated with duodenal ulcer, esophagitis and gastritis.[1]

Anwendung

Oxethazaine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).[1]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

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Analysenzertifikate (COA)

Lot/Batch Number

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A Pap et al.
Acta medica Academiae Scientiarum Hungaricae, 37(3), 305-313 (1980-01-01)
The effect of submaximal doses of intravenous atropine and their combination with topical anaesthesia of the intestine by oxethazaine-HCl was investigated in conscious rats. I. Basal water, bicarbonate and protein secretion were significantly augmented after diversion of pancreatic juice. On
The abuse potential of oxethazaine: effects of oxethazaine on drug-seeking behavior and analysis of its metabolites in plasma and hair in animal models
Lee Y-S, et al.
Pharmacology, Biochemistry, and Behavior, 105(3), 98-104 (2013)
P A Brennan et al.
The British journal of oral & maxillofacial surgery, 28(1), 26-28 (1990-02-01)
Oxethazaine is the most potent local anaesthetic in use. It is claimed to be 2000 times more potent than lignocaine and 500 times more potent than cocaine as assessed in rabbits eyes. Currently, oxethazaine is used in an antacid preparation
M K Barry et al.
The Journal of surgical research, 58(4), 425-431 (1995-04-01)
The ingestion of a meal stimulates absorption from the jejunal lumen and is dependent on intact neural pathways. Few studies of ileal absorptive responses to a meal have been performed. This study tested two hypotheses: (1) a meal stimulates ileal
Yasusuke Masuda et al.
Journal of pharmacological sciences, 98(2), 181-184 (2005-06-09)
Clomipramine (CLM) and oxethazaine (OXZ) were previously reported to increase portal pressure by contracting portal vein branches (PVBs) in isolated perfused rat liver. In the present study, to characterize the contractile mechanisms, the effects of Y27632, HA1077, staurosporine, papaverine, SKF96365
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