09-230

Anti-phospho-Raptor (Thr706) Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: canine, human
• Speziesreaktivität (Voraussage durch Homologie): horse (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), rat (based on 100% sequence homology)
• Methode(n): dot blot: suitable; western blot: suitable
• NCBI-Hinterlegungsnummer: NP_065812
• UniProt-Hinterlegungsnummer: Q8N122
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: phosphorylation (pThr706)
• Angaben zum Gen: bovine ... Rptor(507056) ; human ... RPTOR(57521)

Beschreibung

Allgemeine Beschreibung

Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.

Spezifität

This antibody recognizes Raptor phosphorylated at Thr706.

Immunogen

Epitope: Ser706

KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706.

Anwendung

Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB.

Qualität

Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Zielbeschreibung

~ 150 kDa

Physikalische Form

Purified rabbit serum in PBS with 0.05% sodium azide.

Hinweis zur Analyse

Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable