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888787D

Avanti

PAMPA Lipid Blend I

Avanti Research™ - A Croda Brand

Synonym(e):

PAMPA Lipid Blend I, DOPC:Stearic Acid (80:20, w/w) in Dodecane with 1% Ethanol for use in PAMPA assay, dodecane

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About This Item

UNSPSC-Code:
12352211
NACRES:
NA.25

Form

liquid

Verpackung

pkg of 1 × 3 mL (888787D-150mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand

Konzentration

50 mg/mL (888787D-150mg)

Anwendung(en)

microbiology

Lipid-Typ

phospholipids

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

PAMPA Lipid Blend I is a lipid solution in dodecane/ethanol. Once opened, the contents of the glass ampoule should be transferred to a glass container with PTFE-lined screw cap closure for storage at -20°C. The transfer should be performed with a glass syringe or pipette. The solution should not contact plastic, i.e., do not transfer with plastic pipette tip or store in plastic vials.

Anwendung

The PAMPA Lipid Blend I has been used in the parallel artificial membrane permeability assay (PAMPA) for the formation of artificial membrane.

Biochem./physiol. Wirkung

The parallel artificial membrane permeability assay (PAMPA) is useful to study the oral absorption of drugs. It helps in specifying passive transcellular diffusion.

Verpackung

5 mL Clear Glass Sealed Ampule (888787D-150mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H304

Gefahreneinstufungen

Asp. Tox. 1

Zusätzliche Gefahrenhinweise

EUH066

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Li Di et al.
European journal of medicinal chemistry, 38(3), 223-232 (2003-04-02)
The recent advances in high throughput screening for biological activities and combinatorial chemistry have greatly expanded the number of drug candidates. Rapid screening for BBB penetration potential early in drug discovery programs provides important information for compound selection and guidance
Fangzhou Xie et al.
Bioorganic chemistry, 92, 103273-103273 (2019-09-21)
Protein tyrosine phosphatase 1B (PTP1B), a key negative regulator of insulin signaling, is considered as a promising and validated therapeutic target for type 2 diabetes mellitus (T2DM) and obesity. Upon careful study, a series of 2-ethoxy-4-(methoxymethyl)benzamide and 2-ethoxy-5-(methoxymethyl)benzamide analogs designed
High-throughput artificial membrane permeability studies in early lead discovery and development
Pharmacokinetic optimization in drug research (2001)
Fangzhou Xie et al.
European journal of medicinal chemistry, 164, 408-422 (2019-01-07)
Protein tyrosine phosphatase 1B (PTP1B) has been considered as a promising therapeutic target for type 2 diabetes mellitus (T2DM) and obesity due to its key regulating effects in insulin signaling and leptin receptor pathways. In this work, a series of

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