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Sigma-Aldrich

Diisopropylcarbodiimide solution

1 M in dichloromethane

Synonym(e):

Diisopropylmethanediimine

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About This Item

Lineare Formel:
C7H14N2
CAS-Nummer:
693-13-0
MDL-Nummer:
MFCD00065689
UNSPSC-Code:
12352200

Form

liquid

Eignung der Reaktion

reaction type: Coupling Reactions

Konzentration

1 M in dichloromethane

Brechungsindex

n/D 1.4251

Dichte

1.2231

Anwendung(en)

peptide synthesis

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

InChIKey

BDNKZNFMNDZQMI-UHFFFAOYSA-N

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Allgemeine Beschreibung

DIC is an abbreviated form of N,N′-diisopropylcarbodiimide. It plays a role in the cyclization of N-(β-hydroxy)amides to form 2-oxazolines.

Anwendung

  • Alternative to dicyclohexylcarbodiimide in peptide synthesis.
  • Coupling reagent for peptide syntheses.
  • DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.
Valuable reagent offered as a solution in dichloromethane for more convenient handling.

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

38370

N,N′-Diisopropylcarbodiimid, purum, ≥98.0% (GC)

D125407

N,N′-Diisopropylcarbodiimid, 99%

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Carc. 2 - Eye Dam. 1 - Flam. Liq. 3 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 3

Flammpunkt (°F)

91.4 °F

Flammpunkt (°C)

33 °C

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