900757

Sodium pyridine-2-sulfinate

• Synonym(e): 2-Pyridinesulfinic acid, Sodium salt, Willis 2-pyridylsulfinates H
• Empirische Formel (Hill-System): C₅H₄NNaO₂S
• CAS-Nummer: 24367-66-6
• Molekulargewicht: 165.15
• UNSPSC-Code: 12352101
• NACRES: NA.22

Eigenschaften

• Form: powder or crystals
• Qualitätsniveau: 100
• Eignung der Reaktion: reaction type: C-C Bond Formation
• mp (Schmelzpunkt): 292 °C
• InChI: 1S/C5H5NO2S.Na/c7-9(8)5-3-1-2-4-6-5;/h1-4H,(H,7,8);/q;+1/p-1
• InChIKey: HQCGASCBCQJRDJ-UHFFFAOYSA-M

Beschreibung

Anwendung

This 2-pyridylsulfinate enables Suzuki-Miyaura cross coupling with aryl halides to access diverse pyridine derivatives as reported by the laboratory of Michael Willis.. No longer impeded by unstable 2-pyridyl boronates, the sulfinate alternatives provide Pd-catalyzed coupling routes to therapeutically valuable pyridine rings.

Sonstige Hinweise

• Technology Spotlight: Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions.
• Pyridine Sulfinates as General Nucleophilic Coupling Partners in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable