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Merck

900628

Sigma-Aldrich

Gelatine-Methacryloyl

gel strength 90-110 g Bloom, degree of substitution 60%

Synonym(e):

GelMa, Gelatine-Methacrylamid, Gelatine-Methacrylat

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1 G
CHF 193.00

CHF 193.00


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1 G
CHF 193.00

About This Item

Lineare Formel:
(C40H59N11O13)n
UNSPSC-Code:
12352202
NACRES:
NA.23

CHF 193.00


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Qualitätsniveau

Form

solid

Lagertemp.

2-8°C

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Anwendung

Gelatin methacrylate can be used to form cross-linked hydrogels for tissue engineering[1] and 3D printings.[2][3][4] It has been used for endothelial cell morphogenesis,[5] cardiomyocytes,[6] epidermal tissue,[7] injectable tissue constructs,[8] bone differentiation,[9] and cartilage regeneration.[10] Gelatin-methacrylate has been explored in drug delivery applications in the form of microspheres[11] and hydrogels.[12]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Xin Zhao et al.
Advanced healthcare materials, 5(1), 108-118 (2015-04-17)
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels used to support epidermal regeneration are mainly collagen- or gelatin-based, which mimic the natural dermal extracellular matrix but often suffer from insufficient and uncontrollable mechanical and degradation properties. In
Kristel W M Boere et al.
Acta biomaterialia, 10(6), 2602-2611 (2014-03-05)
Hydrogels can provide a suitable environment for tissue formation by embedded cells, which makes them suitable for applications in regenerative medicine. However, hydrogels possess only limited mechanical strength, and must therefore be reinforced for applications in load-bearing conditions. In most
Kelly M C Tsang et al.
Advanced functional materials, 25(6), 977-986 (2015-09-04)
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization in vitro. Researchers have incorporated photodegradable moieties into synthetic polymeric hydrogels as a means of achieving spatiotemporal control over material properties. In this study protein-based photodegradable hydrogels
Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta NV, et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
Jason W Nichol et al.
Biomaterials, 31(21), 5536-5544 (2010-04-27)
The cellular microenvironment plays an integral role in improving the function of microengineered tissues. Control of the microarchitecture in engineered tissues can be achieved through photopatterning of cell-laden hydrogels. However, despite high pattern fidelity of photopolymerizable hydrogels, many such materials

Artikel

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

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