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24880

Sigma-Aldrich

5-Chlor-7-iod-8-chinolinol

≥95.0% (HPLC)

Synonym(e):

5-Chlor-7-iod-chinolin-8-ol, 5-Chlor-8-hydroxy-7-iod-chinolin, Clioquinol

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About This Item

Empirische Formel (Hill-System):
C9H5ClINO
CAS-Nummer:
130-26-7
Molekulargewicht:
305.50
Beilstein:
153637
EG-Nummer:
204-984-4
MDL-Nummer:
MFCD00006787
UNSPSC-Code:
12352100
PubChem Substanz-ID:
57648095
NACRES:
NA.22

Assay

≥95.0% (HPLC)

Form

powder

Löslichkeit

dioxane: soluble 0.5 g/10 mL, clear, faintly yellow to yellow

SMILES String

Oc1c(I)cc(Cl)c2cccnc12

InChI

1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

InChIKey

QCDFBFJGMNKBDO-UHFFFAOYSA-N

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Allgemeine Beschreibung

5-Chloro-7-iodo-8-quinolinol is an antibiotic with metal-binding properties and exhibits anticancer activity in vitro and in vivo. 5-Chloro-7-iodo-8-quinolinol, its glucuronide and sulfate in serum, urine and milk has been quantitated by gas chromatography.

Anwendung

5-Chloro-7-iodo-8-quinolinol has been used in analysis of intracellular free zinc ions with the FluoZin-3 probes using fluorescence microscopy.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Fluo 3-AM ≥90% (TLC)

Sigma-Aldrich

73881

Fluo 3-AM

Chloroquin -diphosphat (Salz) powder or crystals, 98.5-101.0% (EP)

Sigma-Aldrich

C6628

Chloroquin -diphosphat (Salz)

A gas chromatographic determination method of 5-chloro-7-iodo-8-quinolinol and its conjugates in biological fluids.
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