1.06447

Citrate de sodium tribasique dihydrate

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS, E 331

• Synonyme(s) : Acide citrique trisodium salt dihydrate, Citrate trisodique dihydrate
• Formule linéaire : HOC(COONa)(CH₂COONa)₂ · 2H₂O
• Numéro CAS: 6132-04-3
• Poids moléculaire : 294.10
• Numéro Beilstein : 6104939
• Numéro MDL: MFCD00150031
• Code UNSPSC : 12352107
• Numéro E: E331
• Numéro de classement CE : 200-675-3

Propriétés

• Agence: BP; ChP; JP; Ph. Eur.; USP; suitable for SM 4500 - NH3
• Niveau de qualité: 500
• Gamme de produits: EMPROVE^® EXPERT
• Forme: solid
• Caractéristiques: RNase and DNase free
• pH: 7.5-9.0 (25 °C, 50 g/L in H₂O)
• Pf: 150 °C (anhydrous substance); >300 °C (lit.)
• Application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• Température de stockage: 2-30°C
• Chaîne SMILES: O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
• Clé InChI: NLJMYIDDQXHKNR-UHFFFAOYSA-K

Description

Description générale

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium citrate dihydrate is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable