X7375

Xantina

≥99%

• Sinônimo(s): 2,6-Di-hidroxipurina
• Fórmula empírica (Notação de Hill): C₅H₄N₄O₂
• Número CAS: 69-89-6
• Peso molecular: 152.11
• Beilstein: 8733
• Número CE: 200-718-6
• Número MDL: MFCD00078453
• Código UNSPSC: 41106305
• ID de substância PubChem: 24902156
• NACRES: NA.51

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 300
• Ensaio: ≥99%
• forma: powder
• solubilidade: 1 M NaOH: soluble 50 mg/mL, clear to slightly hazy; NH₄OH: freely soluble; NaOH: freely soluble
• cadeia de caracteres SMILES: O=C1NC(=O)c2nc[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
• chave InChI: LRFVTYWOQMYALW-UHFFFAOYSA-N

Descrição

Descrição geral

Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid. Xanthine derivatives are present in coffee, tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds.

Aplicação

Xanthine has been used in a nonradiolabled substrate mix in an Aspergillus nidulans transport assay. It has also been used as a substrate for xanthine oxidase for superoxide anion generation in gill cells and algal cells.

Ações bioquímicas/fisiológicas

A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples. Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves