X2502

Xanthine sodium salt

≥99%

• Sinônimo(s): 2,6-Dihydroxypurine
• Fórmula empírica (Notação de Hill): C₅H₃N₄NaO₂
• Número CAS: 1196-43-6
• Peso molecular: 174.09
• Número MDL: MFCD00069699
• Código UNSPSC: 41106305
• ID de substância PubChem: 24902137
• NACRES: NA.51

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• Ensaio: ≥99%
• forma: powder
• Impurezas: ≤4% total solvent
• solubilidade: dilute NaOH: soluble, clear to slightly hazy
• cadeia de caracteres SMILES: [Na].O=C1NC(=O)c2[nH]cnc2N1
• InChI: 1S/C5H4N4O2.Na.H/c10-4-2-3(7-1-6-2)8-5(11)9-4;;/h1H,(H3,6,7,8,9,10,11);;
• chave InChI: JAZQMXVZANZJSO-UHFFFAOYSA-N

Descrição

Descrição geral

Xanthine is an intermediate of purine nucleotide metabolism. It is found in most body tissues and fluids. Xanthine derivatives are present in coffee, tea, and chocolate.

Aplicação

Xanthine sodium salt has been used as a component of substrate solution for xanthine oxidase during superoxide dismutase (SOD) assay. It has also been used as a supplement in a special-conditioned medium to culture Swiss 3T3 fibroblasts stably transfected with tetracycline (tet)-controlled transactivator and transactivator-controlled tissue transglutaminase cDNA [39] constructs (clone TG3).

Ações bioquímicas/fisiológicas

Xanthine acts as a substrate for xanthine oxidase. It elevates cellular cyclic AMP levels by preventing its breakdown and metabolism by inhibition of tissue phosphodiesterases. Xanthine also exhibits anti-inflammatory properties either by the release of anti-inflammatory cytokines or gene transcription regulation or histone deacetylase activation. All these properties of xanthine aid in the relaxation of smooth muscles of the bronchial tree.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Warning
• Frases de perigo: H371
• Declarações de precaução: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Classificações de perigo: STOT SE 2
• Órgãos-alvo: Eyes,Central nervous system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves