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UC448

Sigma-Aldrich

Paracetamol sulfate potassium salt

solid, ≥97% (HPLC)

Sinônimo(s):

4-Acetamidophenol sulfate ester potassium salt, Acetaminophen sulfate potassium salt, N-(4-Sulfoxyphenyl)acetamide monopotassium salt

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About This Item

Fórmula empírica (Notação de Hill):
C8H8KNO5S
Número CAS:
Peso molecular:
269.32
Número MDL:
Código UNSPSC:
12161501
ID de substância PubChem:
NACRES:
NA.77

Ensaio

≥97% (HPLC)

forma

solid

cor

white to off-white

pf

163 °C

solubilidade

H2O: soluble

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1

chave InChI

AJYPYWFCUWHZMZ-UHFFFAOYSA-M

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Descrição geral

Paracetamol is an aminophenol derivative. It functions as an analgesic and antipyretic drug, which has weak inflammatory effect. Paracetamol is used to treat pyrexia and mild to moderate pain. It might inhibit atherosclerosis through its antioxidant activity.

Aplicação

Paracetamol sulfate potassium salt has been used as a standard for HPLC assays of acetaminophen.

Ações bioquímicas/fisiológicas

Phase II metabolite of paracetamol.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota de preparo

Paracetamol sulfate potassium salt is soluble in water.

Outras notas

Occasionally, it may be necessary to supply as the sodium salt

Pictogramas

CorrosionExclamation mark

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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D Bougie et al.
Blood, 97(12), 3846-3850 (2001-06-05)
In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in
Paracetamol: past, present, and future.
Prescott LF
American Journal of Therapeutics, 7(2), 143-147 (2000)
Hayati Filik et al.
Chemical & pharmaceutical bulletin, 54(6), 891-896 (2006-06-07)
In the present paper, conventional spectrophotometry in conjunction with cloud point extraction-preconcentration were investigated as alternative methods for paracetamol (PCT) assay in urine samples. Cloud point extraction (CPE) was employed for the preconcentration of p-aminophenol (PAP) prior to spectrophotometric determination
H Xiong et al.
The Journal of pharmacology and experimental therapeutics, 295(2), 512-518 (2000-10-25)
Previous studies have demonstrated that phenobarbital treatment impairs the biliary excretion of acetaminophen glucuronide (AG), although the transport system(s) responsible for AG excretion into bile has not been identified. Initial studies in rat canalicular liver plasma membrane vesicles indicated that
Caroline D van der Marel et al.
European journal of clinical pharmacology, 59(3), 243-251 (2003-05-23)
Data concerning metabolism of paracetamol in infants are scant. Previous studies have examined urinary metabolite recovery rates after a single dose of paracetamol in either neonates (<6 weeks) or children (3-9 years). There are no studies investigating infants. Infants (

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