T3309
Transferrina
≥98%
Sinônimo(s):
Siderofilina, parcialmente saturada
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About This Item
Produtos recomendados
fonte biológica
human
Nível de qualidade
Ensaio
≥98%
forma
powder
Teor de ferro
300-600 ppm
técnica(s)
cell culture | stem cell: suitable
Impurezas
≤1.0 EU/mg endotoxin
nº de adesão UniProt
temperatura de armazenamento
2-8°C
Informações sobre genes
human ... TF(7018)
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Descrição geral
Transferrin is an 80 kDa serum glycoprotein, which has an half-life of 8 to 10 days. The gene is located on human chromosome 3q22.1. Transferrin is expressed in hepatocytes.
Aplicação
Transferrin has been used:
- in isolation of epidermal stem cells and cell expansion
- to study the effect of compound treatment on transferrin uptake
- for transferrin uptake and confocal imaging
Ações bioquímicas/fisiológicas
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. Mutations in this gene is associated with atransferrinemia. Transferrin is required for fetal development. It is non immunogenic and transferrin-conjugated drugs inhibits cardiotoxicity and drug resistance.
Transferrin was shown to promote the proliferation of human lymphocytes. This effect is directly proportional to the level of iron present.
Nota de análise
Pureza por eletroforese em gel de agarose.
Exoneração de responsabilidade
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Certificados de análise (COA)
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The effect of different forms of iron and iron-binding proteins on the proliferative response of human lymphocytes to phytohaemagglutinin (PHA) has been studied. Transferrin enhanced proliferation, the effect being proportional to the degree of iron saturation up to 100%, but
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PLoS ONE, 8(11), e80269-e80269 (2013)
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