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SMB00607

Sigma-Aldrich

Amoxicillin trihydrate: potassium clavulanate (4:1)

Sinônimo(s):

Amoxicillin Trihydrate: Potassium Clavulanate

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About This Item

Código UNSPSC:
51285005
NACRES:
NA.85

forma

powder

Nível de qualidade

200

condição de armazenamento

(Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.)

cor

white to yellow

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria

Modo de ação

cell wall synthesis | interferes

temperatura de armazenamento

2-8°C

Categorias relacionadas

Descrição geral

Amoxicillin trihydrate is a semisynthetic antibiotic, that is used as a medicine.

Aplicação

Amoxicillin trihydrate: potassium clavulanate (4:1) has been used to study its effect on the viral déjà vu disease (neonatal intracerebral (i.c.) infection) in mice model.

Ações bioquímicas/fisiológicas

Amoxicillin trihydrate is a broad-spectrum, β-lactam antibiotic. It inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. Since amoxicillin is degraded by β-lactamases, it does not show activity against bacteria which produce these enzymes.

Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by β-lactamase enzymes. This increases amoxicillin′s antibacterial activity against bacteria normally resistant to β-lactam antibiotics.

Embalagem

1G

Componentes

Material is a powdered mixture of 4 parts amoxicillin trihydrate to 1 part potassium clavulanate.

Armazenamento e estabilidade

Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.

Pictogramas

FlameHealth hazard
GHS02,GHS08

Palavra indicadora

Danger

Frases de perigo

H228,H252,H317,H334

Classificações de perigo

Flam. Sol. 2 - Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1

Perigos de suplementos

EUH014,EUH044

Código de classe de armazenamento

4.2 - Pyrophoric and self-heating hazardous materials

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Preparation and characterization of Sn/Zn/TiO2 photocatalyst for enhanced amoxicillin trihydrate degradation
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A P Ball et al.
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H C Neu et al.
Antimicrobial agents and chemotherapy, 10, 407-410 (1970-01-01)
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Amoxycillin, an acid stable semisynthetic penicillin shown to be effective against a wide range of infections when given orally, is now available for intramuscular and intravenous injection. Amoxycillin has an antibacterial spectrum and level of activity essentially the same as
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