SAB4500839
Anti-FAP-1 antibody produced in rabbit
affinity isolated antibody
Sinônimo(s):
PTP-BAS, PTP1E, PTPL1, PTPN13, α subunit, DPPIV, FAPA, SEPRASE, fibroblast activation protein
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100 μG
R$ 4.655,00
R$ 4.655,00
Disponível para enviar em22 de abril de 2025Detalhes
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100 μG
R$ 4.655,00
About This Item
R$ 4.655,00
Disponível para enviar em22 de abril de 2025Detalhes
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
conjugado
unconjugated
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
Formulário
buffered aqueous solution
peso molecular
antigen 87 kDa
reatividade de espécies
human, mouse, rat
concentração
~1 mg/mL
técnica(s)
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... FAP(2191)
Categorias relacionadas
Descrição geral
Fibroblast activation protein 1 (FAP-1) is a membrane-associated protein tyrosine phosphatase. It is made up of an ezrin-like cytoskeleton binding domain, six PSD95/Dlg/Z-1 homology (PDZ) domains, and a leucine zipper motif. The FAP-1 gene is located on the human chromosome at 4q21.3. Anti-FAP-1 antibody detects endogenous levels of total FAP-1 protein.
Imunogênio
The antiserum was produced against synthesized peptide derived from human FAP-1.
Immunogen Range: 331-380
Immunogen Range: 331-380
Aplicação
Anti-FAP-1 antibody produced in rabbit has been used in western blotting (1: 500) and immunohistochemistry (10 μg/ml)[1].
Ações bioquímicas/fisiológicas
Fibroblast activation protein 1 (FAP-1) is involved in tumorigenesis, apoptosis, cancer progression, and insulin signaling. It acts as a prognostic marker in high-grade serous ovarian cancer and breast cancer. Overexpression of the FAP-1 gene is associated with several human cancers such as hepatocellular, pancreatic, ovarian, hematological, and colon cancer. Mutations in the FAP-1 gene lead to liver and lung cancer.
Características e benefícios
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forma física
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
nwg
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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