S0445

Anti-Serotonin 5-HT_2B Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-5-HT(2B), Anti-5-HT-2B, Anti-5-HT2B
• Número MDL: MFCD01865274
• Código UNSPSC: 12352203

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• reatividade de espécies: human
• disponibilidade: not available in Japan
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-6 μg/mL using human brain, neurons and glia
• nº de adesão UniProt: P41595
• Condições de expedição: wet ice
• temperatura de armazenamento: −70°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... HTR2B(3357) ; mouse ... Htr2b(15559) ; rat ... Htr2b(29581)

Descrição

Descrição geral

Multiplbe genes encode different subtypes of serotonin (5HT) receptor and are species specific. HTR2B is expressed in mammalian brain and is localized to GABA (γ-aminobutyric acid) producing neurons of dorsal hypothalamic nucleus. The HTR2B gene is mapped to human chromosome 2q37.1.

Imunogênio

synthetic peptide corresponding to the second extracellular loop of human serotonin 5-HT_2B receptor, conjugated KLH. The immunizing peptide has 80% homology with the rat gene and 93% homology with the mouse gene.

Ações bioquímicas/fisiológicas

The functions of serotonin (5HT) receptors are associated with sleep disorders, anxiety, depression and schizophrenia.

Descrição-alvo

The Serotonin 5-HT_2B Receptor regulates cardiomyocyte development and growth. Activation of 5-HT_2B receptors may also contribute to initiation of sleep and to theta generation during W and PS under physiological conditions.

forma física

solution in phosphate buffered saline containing ≤0.1% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable