RAB0364
Human MMP-13 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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1 KIT
R$ 3.289,00
R$ 3.289,00
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1 KIT
R$ 3.289,00
About This Item
Código UNSPSC:
41116158
NACRES:
NA.32
R$ 3.289,00
Check Cart for Availability
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reatividade de espécies
human
embalagem
kit of 96 wells (12 strips x 8 wells)
técnica(s)
ELISA: suitable
capture ELISA: suitable
entrada
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 8.23-6000 pg/mL
método de detecção
colorimetric
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
Informações sobre genes
human ... MMP13(4322)
Categorias relacionadas
Descrição geral
The Human MMP-13 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-13 in serum, plasma, cell culture supernatants and urine.
Imunogênio
Recombinant Human MMP13
Aplicação
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Ações bioquímicas/fisiológicas
MMP13 (matrix metalloproteinase 13) functions against different types of ECM (extracellular matrix) components. It gets activated by and activates multiple MMPs and hence, has a central role in the MMP cascade. This protein is frequently expressed in colorectal cancer (CRC) and this expression is linked with poor survival in CRC.[1] MMP13 expression is absent in normal breast tissue, but is present in breast carcinoma suggesting its role in tumorigenesis.[2] The expression of this protein can serve as a marker for tumor invasiveness, as its expression is induced during metastasis of multiple types of cancers, including squamous cell carcinomas of the head and neck and this expression is usually linked to poor prognosis.[3] Missense mutation in this gene results in the autosomal dominant disorder called Missouri type of human spondyloepimetaphyseal dysplasia (SEMDMO), which is characterized by abnormal growth and modeling of vertebrae and long bones. [4]
Outras notas
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Met. Corr. 1
Código de classe de armazenamento
8B - Non-combustible corrosive hazardous materials
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasis.
You Y
Cancer Science null
Yoko Sawada et al.
Experimental and therapeutic medicine, 14(5), 4561-4571 (2017-11-08)
The aim of the present study was to assess the efficacy and safety of the oral administration of
Wen Li et al.
Biomolecules, 9(3) (2019-03-21)
Matrix metalloproteinases (MMPs) are capable of degrading and modifying most components of the extracellular matrix (ECM) and the basal membrane (BM), and play crucial roles in cancer invasion and metastasis. MMP gene expressions were regulated primarily at the transcriptional level
S-S Lin et al.
Osteoarthritis and cartilage, 27(9), 1372-1381 (2019-05-31)
MicroRNA (miRNA)107 expression is downregulated but high mobility group box 1 (HMGB-1), Toll-like receptors (TLRs), and receptor for advanced glycation end products (RAGE) are upregulated in osteoarthritic (OA) cartilage. We investigated mir-107/HMGB-1 signaling in OA after hyperbaric oxygen (HBO) treatment.
MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD(MO).
Kennedy AM
The Journal of Clinical Investigation null
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