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PVP1

Sigma-Aldrich

Poly(vinylpyrrolidone)–Iodine complex

Sinônimo(s):

PVP-Iodine, Polyvinylpyrrolidone Iodine, PVP-I, Povadyne® antiseptic

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About This Item

Número CAS:
25655-41-8
Número MDL:
MFCD00084483
Código UNSPSC:
51102829
ID de substância PubChem:
24899316
NACRES:
NA.85

forma

powder

solubilidade

H2O: 100 mg/mL

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria
fungi
parasites
viruses
yeast

Modo de ação

protein synthesis | interferes

cadeia de caracteres SMILES

II.C=CN1CCCC1=O

InChI

1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;

chave InChI

CPKVUHPKYQGHMW-UHFFFAOYSA-N

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Categorias relacionadas

Aplicação

Poly(vinylpyrrolidone)–Iodine complex, or PVP-I, has been used to study microbial decontamination of human donor eyes and the inactivation of infectious hematopoietic necrosis virus.

Ações bioquímicas/fisiológicas

PVP-1 is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine sidechains. It is used as a carbon nanotube coating agent to improve water solubility.

Outras notas

An iodophor; "tamed iodine."
Keep container tightly closed in a dry and well-ventilated place.

Informações legais

Povadyne is a registered trademark of National Patent Development Corp.

Pictogramas

CorrosionEnvironment
GHS05,GHS09

Palavra indicadora

Danger

Frases de perigo

H315,H318,H411

Classificações de perigo

Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

>212.0 °F - Not applicable

Ponto de fulgor (°C)

> 100 °C - Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Yangzi Jiang et al.
Acta biomaterialia, 9(9), 8089-8098 (2013-05-28)
Polyvinylpyrrolidone-iodine (Povidone-iodine, PVP-I) is widely used as an antiseptic agent for lavation during joint surgery; however, the biological effects of PVP-I on cells from joint tissue are unknown. This study examined the biocompatibility and biological effects of PVP-I on cells
Lawrence L Yeung et al.
The Journal of urology, 189(1), 136-140 (2012-11-21)
We defined the relevant skin flora during genitourinary prosthetic surgery, evaluated the safety of chlorhexidine-alcohol for use on the male genitalia and compared chlorhexidine-alcohol to povidone-iodine in decreasing the rate of positive bacterial skin cultures at the surgical skin site
Pracha Nuntnarumit et al.
Infection control and hospital epidemiology, 34(4), 430-432 (2013-03-08)
We conducted a randomized controlled trial in neonates with birth weight greater than or equal to 1,500 g that compared 1% aqueous chlorhexidine gluconate (CHG) with 10% povidone-iodine (PI) as a topical antiseptic. We found 1% CHG to be more
Lina Du et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 20(6), 904-910 (2012-11-01)
In this study, a multifunctional in situ-forming hydrogel (MISG) was prepared as a wound dressing designed to stop bleeding, inhibit inflammation, relieve pain, and improve healing. A mixture of poloxamers 407 and 188 was used for the matrix of the
A Tuna et al.
Australian dental journal, 57(4), 435-439 (2012-11-29)
The aim of this pilot study was to evaluate the effects of mouthrinses containing 7.5% povidone iodine and 0.2% chlorhexidine on bacteraemia following impacted third molar surgery. Thirty-four patients were enrolled in this study. Patients in the first group were
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