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PRS2283

Sigma-Aldrich

Anti-RIP3 antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):

Anti-Receptor-Interacting serine-threonine kinase 3

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About This Item

Número MDL:
MFCD03097232
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

peso molecular

predicted mol wt 57 kDa

reatividade de espécies

rat, human, mouse

técnica(s)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

nº de adesão UniProt

Q9QZL0

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Ripk3(56532)

Imunogênio

a peptide corresponding to amino acids 473-486 of murine RIP3.

Aplicação

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Ligação

The action of this antibody can be blocked using blocking peptide SBP2283.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Imene Jaadane et al.
Scientific reports, 10(1), 6733-6733 (2020-04-23)
Exposure Limit Values (ELV) for artificial lighting were defined in order to prevent light-induced damage to the retina. The evaluation of the lighting devices include the correction of their spectra by the B(λ) function or blue light hazard function, representing
Xia-Lian Wu et al.
Nature communications, 12(1), 1627-1627 (2021-03-14)
RIPK3 amyloid complex plays crucial roles during TNF-induced necroptosis and in response to immune defense in both human and mouse. Here, we have structurally characterized mouse RIPK3 homogeneous self-assembly using solid-state NMR, revealing a well-ordered N-shaped amyloid core structure featured
Douglas Ruhl et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(15), 2951-2964 (2019-02-09)
Ototoxic side effects of cisplatin and aminoglycosides have been extensively studied, but no therapy is available to date. Sensory hair cells, upon exposure to cisplatin or aminoglycosides, undergo apoptotic and necrotic cell death. Blocking these cell death pathways has therapeutic
Lvshuang Liao et al.
Acta biochimica et biophysica Sinica, 49(10), 879-889 (2017-10-06)
Receptor-interacting protein 3 (RIP3) is an essential component of the necroptosis signaling pathway. Phosphorylation of its downstream target, mixed lineage kinase domain-like protein (MLKL), has been proposed to induce necroptosis by initiating Ca2+ influx. Our previous studies have shown that
Alejandra Daruich et al.
Science advances, 5(1), eaau9940-eaau9940 (2019-01-22)
In retinal detachment (RD), photoreceptor death and permanent vision loss are caused by neurosensory retina separating from the retinal pigment epithelium because of subretinal fluid (SRF), and successful surgical reattachment is not predictive of total visual recovery. As retinal iron
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