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P6777

Sigma-Aldrich

Phenelzine sulfate salt

Sinônimo(s):

Phenelzine hydrogen sulphate

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About This Item

Fórmula empírica (Notação de Hill):
C8H12N2 · H2O4S
Número CAS:
156-51-4
Peso molecular:
234.27
Número CE:
205-856-0
Número MDL:
MFCD00050687
Código UNSPSC:
12352200
ID de substância PubChem:
24278646
NACRES:
NA.77

fonte biológica

synthetic

Ensaio

≥98% (iodine, titration)

Formulário

powder

solubilidade

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

cadeia de caracteres SMILES

NNCCC1=CC=CC=C1.OS(=O)(O)=O

InChI

1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

chave InChI

RXBKMJIPNDOHFR-UHFFFAOYSA-N

Informações sobre genes

human ... MAOA(4128) , MAOB(4129)

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Ações bioquímicas/fisiológicas

Non-selective MAO-A/B inhibitor.

Características e benefícios

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301

Declarações de precaução

P301 + P310

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
BCCK9477
BCCK4308
BCCG9192
BCBN9644V
BCBX0084

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Adeline Su-Yin Ngo et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 6(4), 431-434 (2010-07-24)
Phenelzine is an irreversible monoamine oxidase inhibitor (MAOI). Hypertensive reactions after ingestion of tyramine-rich foods such as cheese are well known. However, a review of the available medical literature found no previous reports of myocardial infarction resulting from the ingestion
Travis Musgrave et al.
Brain, behavior, and immunity, 25(8), 1677-1688 (2011-07-05)
Multiple sclerosis (MS) and the animal model, experimental autoimmune encephalomyelitis (EAE), are both accompanied by motor and non-motor symptoms. Pathological changes in the activities of key neurotransmitters likely underlie many of these symptoms. We have previously described disturbances in the
Marco De Giovanni et al.
Science immunology, 9(93), eadj7363-eadj7363 (2024-03-01)
Peyer's patches (PPs) are lymphoid structures situated adjacent to the intestinal epithelium that support B cell responses that give rise to many intestinal IgA-secreting cells. Induction of isotype switching to IgA in PPs requires interactions between B cells and TGFβ-activating
Marco De Giovanni et al.
Immunity, 56(7), 1548-1560 (2023-06-07)
Cryptococcus neoformans is the leading cause of fungal meningitis and is characterized by pathogenic eosinophil accumulation in the context of type-2 inflammation. The chemoattractant receptor GPR35 is expressed by granulocytes and promotes their migration to the inflammatory mediator 5-hydroxyindoleacetic acid
Ghulam Abbas et al.
Phytotherapy research : PTR, 27(1), 39-45 (2012-03-27)
The current study was aimed at investigating the potential antidepressant activity of Areca catechu nut ethanol extract and its various fractions using behavioral (acute and sub-chronic forced swim tests) and biochemical (monoamines and their metabolite levels using high performance liquid
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