N7660

4-Nitrophenol

chromogenic, liquid

• Sinônimo(s): p-Nitrophenol solution
• Fórmula empírica (Notação de Hill): C₆H₅NO₃
• Número CAS: 100-02-7
• Peso molecular: 139.11
• Número MDL: MFCD00007331
• Código UNSPSC: 12352204
• eCl@ss: 39032018
• ID de substância PubChem: 57654462
• NACRES: NA.28

Propriedades

• Nome do produto: 4-Nitrophenol solution, 10 mM
• Formulário: liquid
• Nível de qualidade: 200
• concentração: 10 mM
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H
• chave InChI: BTJIUGUIPKRLHP-UHFFFAOYSA-N
• Informações sobre genes: human ... UGT1A4(54657)

Descrição

Descrição geral

4-Nitrophenol is a phenolic compound present as a chemical intermediate and breakdown product during the production of organophosphorus insecticide derivatives of parathion. It is an intermediate during the synthesis of paracetamol.[1] 4-Nitrophenol is a chromogenic catalytic by product of the synthetic substrate 4-nitrophenyl phosphate. It is majorly used as a reference standard in alkaline phosphatase assay.[2] 4-Nitrophenol is nonbiodegradable and its derivatives are used for herbicide and fungicide production.[3]

Aplicação

4-Nitrophenol solution has been used:

• in the generation of standard curve for quantifying alkaline phosphatase activity of mesenchymal stem cells[4]
• bone marrow stromal cells (BMSCs)[5]
• for quantifying β-hexosaminidase activity in HeLa cells[6]
• as a standard for calorimetric determination of alkaline phosphatase activity at 405 nm[7]
• for assessing the β-hexosamindase activity[8]

Nota de preparo

Prepared as a 1.39 mg/ml solution suitable for use as a calibrator in alkaline phosphatase assays (such as Bessey-Lowry-Brock method) using p-nitrophenol phosphate as a substrate.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)