N6664

Neurodazine

≥98% (HPLC)

• Sinônimo(s): 2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H imidazole
• Fórmula empírica (Notação de Hill): C₂₇H₂₁ClN₂O₃
• Número CAS: 937807-66-4
• Peso molecular: 456.92
• Número MDL: MFCD08906055
• Código UNSPSC: 12352203
• ID de substância PubChem: 329818668
• NACRES: NA.25

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• cor: yellow
• solubilidade: DMSO: >20 mg/mL
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: COc1ccc(cc1)-c2nc([nH]c2-c3ccc(OC)cc3)-c4ccc(o4)-c5cccc(Cl)c5
• InChI: 1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)
• chave InChI: FEEOFPAEDSMOTO-UHFFFAOYSA-N

Descrição

Ações bioquímicas/fisiológicas

Neurodazine is a promoter of neurogenesis. It induces a generation of new nerve cells from skeletal muscle fibers both immature, differentiated myotubes and mature skeletal muscle. Neurodazine promotes the expression of neuron-specific markers in treated C2C12 cells (neurogenesis). In addition, in conjunction with a microtubule-destabilizing agent, Neurodazine allows neurogenic conversion of both differentiated immature myotubes and mature skeletal muscle. Neurodazine is a potential alternative approach to using stem cells.

Neurodazine is a promoter of neurogenesis; induces generation of new nerve cells from skeletal muscle fibers both immature differentiated myotubes and mature skeletal muscle; a potential alternative approach to using stem cells.

Informações de segurança

• Pictogramas: GHS06,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H301,H318,H413
• Declarações de precaução: P264 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P405
• Classificações de perigo: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Dam. 1
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges