M6625
6-Mercaptoguanosine
≥98%
Sinônimo(s):
2-Amino-6-mercaptopurine riboside, 6-Mercapto-2-aminopurine riboside, 6-Thioguanosine
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About This Item
Fórmula empírica (Notação de Hill):
C10H13N5O4S
Número CAS:
Peso molecular:
299.31
Número CE:
Número MDL:
Código UNSPSC:
12352204
Produtos recomendados
Ensaio
≥98%
cadeia de caracteres SMILES
Nc1nc(S)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1
substituído por
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Christian Reichardt et al.
The journal of physical chemistry. B, 115(12), 3263-3270 (2011-03-10)
Patients treated with the immunosuppressant and anticancer drugs 6-thioguanine, azathioprine, or mercaptopurine can metabolize and incorporate them in DNA as 6-thioguanosine. The skin of these patients is sensitive to UVA radiation, and long-term treatment can result in extremely high incidence
Monique Akoachere et al.
The Journal of biological chemistry, 282(16), 12112-12118 (2007-02-14)
Germination of Bacillus anthracis spores into the vegetative form is an essential step in anthrax pathogenicity. This process can be triggered in vitro by the common germinants inosine and alanine. Kinetic analysis of B. anthracis spore germination revealed synergy and
Qinguo Zheng et al.
Bioorganic & medicinal chemistry letters, 13(19), 3141-3144 (2003-09-03)
The preparation of N(2)-phenoxylacetyl-S(6)-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its subsequent incorporation into oligoribonucleotides is described. The identity of the oligonucleotides was confirmed by UV spectrophotometry and nucleoside composition analysis.
N T Vethe et al.
Scandinavian journal of clinical and laboratory investigation, 68(4), 277-285 (2008-07-09)
Depletion of guanine and deoxyguanine nucleotides by inhibition of inosine 5'-monophosphate dehydrogenase (IMPDH, EC 1.1.1.205) or introduction of 6-thioguanine nucleotide antimetabolites are two principles of retarding cell proliferation by interference with the cellular purine nucleotide pool. IMPDH activity may be
S Basu et al.
Nature structural biology, 5(11), 986-992 (1998-11-10)
Metal ions are essential for the folding and activity of large catalytic RNAs. While divalent metal ions have been directly implicated in RNA tertiary structure formation, the role of monovalent ions has been largely unexplored. Here we report the first
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