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Documentos Principais

L7900

Sigma-Aldrich

Sodium DL-lactate solution

synthetic, syrup, BioXtra, suitable for mouse embryo cell culture, 60 % (w/w)

Sinônimo(s):

DL-Lactic acid sodium salt

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About This Item

Fórmula linear:
CH3CH(OH)COONa
Número CAS:
Peso molecular:
112.06
Beilstein:
4332999
Número CE:
Número MDL:
Código UNSPSC:
12352207
ID de substância PubChem:
NACRES:
NA.75
Preço e disponibilidade não estão disponíveis no momento.

fonte biológica

synthetic

Nível de qualidade

linha de produto

BioXtra

Formulário

syrup

concentração

60 % (w/w)

técnica(s)

cell culture | embryo: suitable

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[Na+].CC(O)C([O-])=O

InChI

1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1

chave InChI

NGSFWBMYFKHRBD-UHFFFAOYSA-M

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Aplicação

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). This mixed isomer lactate has been qualified for use in mouse embryo culture. Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.

produto relacionado

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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L J Edwards et al.
Molecular reproduction and development, 50(4), 434-442 (1998-07-21)
Although intracellular pH (pHi), is a regulator of numerous biological processes, it has received relatively little attention with regard to the physiology of the mammalian preimplantation embryo. Interestingly, there is some controversy as to whether the early embryo can recover
M Lane et al.
Biology of reproduction, 62(1), 16-22 (1999-12-28)
This study was an investigation of the interaction of lactate on pyruvate and glucose metabolism in the early mouse embryo. Pyruvate uptake and metabolism by mouse embryos were significantly affected by increasing the lactate concentration in the culture medium. In
Emmi Helle et al.
Frontiers in cell and developmental biology, 9, 715093-715093 (2021-08-24)
Cell-cell interactions are crucial for organ development and function. In the heart, endothelial cells engage in bidirectional communication with cardiomyocytes regulating cardiac development and growth. We aimed to elucidate the organotypic development of cardiac endothelial cells and cardiomyocyte and endothelial
Marek Nalos et al.
Critical care (London, England), 18(2), R48-R48 (2014-03-29)
Acute heart failure (AHF) is characterized by inadequate cardiac output (CO), congestive symptoms, poor peripheral perfusion and end-organ dysfunction. Treatment often includes a combination of diuretics, oxygen, positive pressure ventilation, inotropes and vasodilators or vasopressors. Lactate is a marker of
Wenqian Yuan et al.
Food microbiology, 30(2), 448-452 (2012-03-01)
The aim of the present study was to determine the survival of Salmonella Typhimurium adapted with sodium lactate (NaL), potassium lactate/sodium acetate mixture (KL/NaA) or sodium acetate (NaA) in simulated gastric fluid (SGF) and during heat treatment. NaL-, KL/NaA- and

Artigos

Mouse embryo media and embryo validated reagents for transgenic mouse embryo culture

Questions

1–2 of 2 Questions  
  1. Is this product produced from Genetically Modified organisms (GMO's)?

    1 answer
    1. This product is synthetically produced.

      Helpful?

  2. Hi, Could you tell me what is the concentration of the solution in M (or mM) please? Thank you

    1 answer
    1. The concentration of this product changes slightly from lot to lot. A solution of precisely 60% has a molarity of 7.0 M based on a density of 1.31 g/ml and a molecular weight of 112.1. Please see the link below to review a sample Certificate of Analysis:
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/L7900-100ML0000229622.pdf

      Helpful?

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