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L6649

Sigma-Aldrich

Lonomycin A sodium salt from Streptomyces ribosidificus

90-95% (TLC)

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About This Item

Fórmula empírica (Notação de Hill):
C44H75NaO14
Número CAS:
Peso molecular:
851.05
Beilstein:
4122659
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:

Ensaio

90-95% (TLC)

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[Na+].CO[C@H]1C[C@]2(CC[C@](C)(O2)[C@H]3CC[C@](C)(O3)[C@@H]4O[C@H]([C@H](OC)[C@@H]4C)[C@H]5O[C@](C)(O)[C@H](C)[C@@H](OC)[C@@H]5C)O[C@@H]([C@@H]1C)[C@@H](C)[C@H]6O[C@](O)([C@H](C)[C@@H](OC)[C@H]6C)[C@H](C)C([O-])=O

InChI

1S/C44H76O14.Na/c1-21-29(49-12)20-43(56-31(21)22(2)32-23(3)34(51-14)27(7)44(48,57-32)28(8)39(45)46)19-18-40(9,58-43)30-16-17-41(10,54-30)38-25(5)35(52-15)37(53-38)36-24(4)33(50-13)26(6)42(11,47)55-36;/h21-38,47-48H,16-20H2,1-15H3,(H,45,46);/q;+1/p-1/t21-,22-,23+,24+,25+,26-,27-,28-,29+,30-,31+,32-,33+,34+,35-,36+,37-,38-,40+,41+,42+,43-,44-;/m1./s1

chave InChI

PIKGYGHAIOUQMF-SZCYNZSUSA-M

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Pictogramas

Skull and crossbones

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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[Application of nuclear magnetic resonance to bio-organic chemistry].
J Y Lallemand
Bulletin et memoires de l'Academie royale de medecine de Belgique, 137(8-9), 453-456 (1982-01-01)
A Saito et al.
Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 264(3-4), 446-454 (1987-05-01)
The inhibition of Toxoplasma multiplication inside cells does not correlate with an enhanced release of oxygen intermediates except in the case of peritoneal macrophages treated with Obioactin. The inhibition observed in alveolar macrophages treated with Obioactin, in kidney cells treated
B Marks et al.
Current biology : CB, 8(13), 740-749 (1998-07-04)
Following exocytosis at the synapse, synaptic vesicle components are recovered by endocytosis. Morphological analysis has suggested that this occurs by a clathrin-mediated pathway, and the GTPase dynamin is thought to be involved in 'pinching off' endocytosing vesicles. The finding that
D S Hoover et al.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 8(12), 1371-1380 (1998-01-07)
Expression of Pim-1, an oncogenic serine/threonine kinase, is highly regulated at the transcriptional, posttranscriptional, and posttranslational levels. Here, we report that expression of Pim-1 kinase is additionally regulated at the translational level. Pim-1 protein expression did not increase in Hut-78
M Stoeck et al.
Journal of cellular physiology, 151(1), 8-12 (1992-04-01)
Murine thymocytes were stimulated with the protein kinase C activating agents Phorbol-12-myristate-13-acetate (PMA) or a more physiological membrane permeant diacylglycerol (dioctanoyl-sn-glycerol, DiC8) in the presence or absence of exogenous lymphokines (rIL-1 beta, rIL-2). Whereas PMA directly induced reactivity to rIL-2

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