The method to determine isotopic purity is Mass Spectrometry. This product is an M-Clarity level 200 item. The analytical methods are considered proprietary. Please see the link below to a sample Certificate of Analysis that notes they method:
https://www.sigmaaldrich.com/certificates/COFA/48/487090/487090-BULK_______MBBC8728__.pdf
487090
Água-18O
99 atom % 18O
Sinônimo(s):
18O Labeled water
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1 G
R$ 10.238,00
About This Item
Fórmula linear:
H218O
Número CAS:
Peso molecular:
20.02
Número MDL:
Código UNSPSC:
12142200
ID de substância PubChem:
NACRES:
NA.12
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descrição
Normalized with respect to hydrogen
Nível de qualidade
pureza isotópica
99 atom % 18O
Formulário
liquid
p.e.
100 °C (lit.)
pf
0 °C (lit.)
densidade
1.11 g/mL at 20 °C (lit.)
alteração de massa
M+2
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
[18OH2]
InChI
1S/H2O/h1H2/i1+2
chave InChI
XLYOFNOQVPJJNP-NJFSPNSNSA-N
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Descrição geral
H2180 is isotopically modified compound consisting of two hydrogen atoms covalently bonded to oxygen-18. It is most convenient to store, transport and use Oxygen-18 in the form of water enriched with this isotope.
Aplicação
O-18 enriched water is used in Positron-Emission Tomography (PET), a nuclear imaging technique that is used to observe metabolic processes in the body as an aid to the diagnosis of disease such as tumors, staging of cancer, metastasis, dementia, etc. H2180 is currently the only potential universal bacterial substrate suitable for stable isotope probing (SIP). It has been used in the quantification of population-specific growth dynamics in benthic bacterial communities in response to changing redox conditions.
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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H H Coenen et al.
Nuclear medicine and biology, 37(7), 727-740 (2010-09-28)
Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide thanks to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals. There is an armamentarium of fluorine-18 ((18)F) tracers that can be used for
Elizabeth A Rettedal et al.
MicrobiologyOpen, 4(2), 208-219 (2015-02-05)
Current limitations in culture-based methods have lead to a reliance on culture-independent approaches, based principally on the comparative analysis of primary semantides such as ribosomal gene sequences. DNA can be remarkably stable in some environments, so its presence does not
Ömer K Coskun et al.
The ISME journal, 13(6), 1546-1559 (2019-02-21)
The benthos in estuarine environments often experiences periods of regularly occurring hypoxic and anoxic conditions, dramatically impacting biogeochemical cycles. How oxygen depletion affects the growth of specific uncultivated microbial populations within these diverse benthic communities, however, remains poorly understood. Here
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