I117

R(+)-IAA-94

≥98% (HPLC), solid

• Sinônimo(s): Indanyloxyacetic acid 94, R(+)-Methylindazone, R(+)-[(6,7-Dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)-oxy]acetic acid
• Fórmula empírica (Notação de Hill): C₁₇H₁₈Cl₂O₄
• Número CAS: 54197-31-8
• Peso molecular: 357.23
• Código UNSPSC: 12352200
• ID de substância PubChem: 24277844
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: solid
• atividade óptica: [α]22/D +36.4°, c = 0.86 in methanol(lit.)
• cor: white
• solubilidade: H₂O: 0.2 mg/mL; 0.1 M NaOH: 2.8 mg/mL; DMSO: >20 mg/mL; ethanol: 20 mg/mL; dilute aqueous acid: insoluble
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: C[C@@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C3CCCC3
• InChI: 1S/C17H18Cl2O4/c1-17(10-4-2-3-5-10)7-9-6-11(23-8-12(20)21)14(18)15(19)13(9)16(17)22/h6,10H,2-5,7-8H2,1H3,(H,20,21)/t17-/m1/s1
• chave InChI: RNOJGTHBMJBOSP-QGZVFWFLSA-N

Descrição

Aplicação

R(+)-IAA-94 has been used as a chloride ion channel inhibitor to study its effects on grepafloxacin uptake by human mononuclear (THP-1) cells [1]. It has also been used as a chloride ion channel inhibitor to study its effects on moxifloxacin uptake by human mononuclear (THP-1) cells.[2]

Características e benefícios

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)