H6666
Keratinocyte Growth Factor human
HumanKine®, >95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture
Sinônimo(s):
FGF-7, KGF
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10 μG
R$ 2.636,00
R$ 2.636,00
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10 μG
R$ 2.636,00
About This Item
R$ 2.636,00
Check Cart for Availability
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Nome do produto
Keratinocyte Growth Factor human, KGF, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
fonte biológica
human
recombinante
expressed in HEK 293 cells
Ensaio
>95% (SDS-PAGE)
Formulário
lyophilized powder
potência
4-20 ng/mL EC50
qualidade
endotoxin tested
peso molecular
dimer 17-30 kDa (glycosylated)
embalagem
pkg of 10 μg
técnica(s)
cell culture | mammalian: suitable
Impurezas
<1 EU/μg
nº de adesão UniProt
temperatura de armazenamento
−20°C
Informações sobre genes
human ... FGF7(2252)
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Descrição geral
Aplicação
Keratinocyte Growth Factor (KGF) human has been used as a component of the keratinocyte differentiation medium.[4]
Ações bioquímicas/fisiológicas
Keratinocyte Growth Factor (KGF) exerts paracrine effects on mesenchymal cells. It exhibits cryoprotective effects on epithelial cells of the lungs, gastrointestinal tract, and the lungs.[1] KGF participates in the activation of IIIb isoform of the fibroblast growth factor (FGF)-receptor 2 (FGFR2-IIIb) present on keratinocytes. This activation further favors proliferation, migration, and survival of keratinocytes.[2]
forma física
Lyophilized from a 0.2 μm filtered solution of 1x PBS.
Nota de preparo
HumanKine Keratinocyte Growth Factor (KGF) is expressed as glycosylated 17 and 30 kDa monomers in human HEK 293 cells. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
Nota de análise
The activity was determined by the dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line).
Informações legais
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
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Preços
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Qandeel Fatima et al.
Open life sciences, 13, 544-552 (2018-12-31)
Autologous skin grafts are used to treat severe burn wounds, however, the availability of adequate donor sites makes this option less practical. Recently, stem cells have been used successfully in tissue engineering and in regenerative medicine. The current study aims
Michael J LaFemina et al.
American journal of physiology. Lung cellular and molecular physiology, 299(6), L724-L734 (2010-09-14)
Keratinocyte growth factor (KGF) has efficacy in several experimental models of lung injury; however, the mechanisms underlying KGF's protective effect remain incompletely understood. This study was undertaken to determine whether KGF augments barrier function in primary rat alveolar epithelial cells
Verônica Chomiski et al.
Acta cirurgica brasileira, 31(8), 505-512 (2016-09-01)
To evaluate the effect of keratinocyte growth factor (KGF) treatment on the expression of wound-healing-related genes in cultured keratinocytes from burn patients. Keratinocytes were cultured and divided into 4 groups (n=4 in each group): TKB (KGF-treated keratinocytes from burn patients)
Susanne Braun et al.
Journal of cell science, 119(Pt 23), 4841-4849 (2006-11-09)
Owing to its potent cytoprotective properties for epithelial cells, keratinocyte growth factor (KGF) is successfully used for the treatment of chemotherapy- and radiotherapy-induced oral mucositis in cancer patients. It is therefore of major interest to determine possible clinical applications of
Umbilical cord tissue derived mesenchymal stem cells can differentiate into skin cells
Fatima Q, et al.
The Open Immunology Journal, 13(1), 544-552 (2018)
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