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H6291

Sigma-Aldrich

Interleukin-1β human

IL-1β, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture, endotoxin tested

Sinônimo(s):

IL-1β, Lymphocyte activating factor

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About This Item

Número MDL:
MFCD00131399
Código UNSPSC:
12352202
NACRES:
NA.77

fonte biológica

human

Nível de qualidade

100

recombinante

expressed in HEK 293 cells

Ensaio

≥95% (SDS-PAGE)

forma

lyophilized powder

potência

≤0.05 ng/mL EC50

qualidade

endotoxin tested

peso molecular

dimer 18-25 kDa (glycosylated)

embalagem

pkg of 10 μg

técnica(s)

cell culture | mammalian: suitable

Impurezas

<1 EU/μg

nº de adesão UniProt

P01584

temperatura de armazenamento

−20°C

Informações sobre genes

human ... IL1B(3553)

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Categorias relacionadas

Ações bioquímicas/fisiológicas

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cell lymphocytes, which then proliferate and secrete interleukin-2 (IL-2). IL-1 is released primarily from stimulated macrophages and monocytes, but has also been shown to be released from several other types and is thought to play a key role in inflammatory and immune responses. Other synonyms for IL-1 include: endogenous pyrogen (EP), mitogenic protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFM), B Cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF) The two closely related agents Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) share 62% homology in amino acid sequence and elicit nearly identical biological responses. IL-1α and IL-1β are both approximately 17 kDa with some heterogeneity in the amount of glycosylation.

forma física

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

Nota de preparo

HumanKine Recombinant Human IL-1β, expressed in human HEK 293 cells, is a glycosylated monomer with a molecular mass of 18-25 kDa. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.

Nota de análise

The activity is determined by the dose-dependent stimulation of the proliferation of mouse D10S cells.

Informações legais

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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