H0536
Hepatocyte Growth Factor Receptor (c-Met)/Fc Chimera human
>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
Sinônimo(s):
HGF Receptor (c-Met)
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100 μG
R$ 5.231,00
R$ 5.231,00
Previsão de entrega em25 de maio de 2025
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100 μG
R$ 5.231,00
About This Item
R$ 5.231,00
Previsão de entrega em25 de maio de 2025
Produtos recomendados
fonte biológica
human
Nível de qualidade
recombinante
expressed in NSO cells
Ensaio
>95% (SDS-PAGE)
Formulário
lyophilized powder
potência
0.1-5 ng/mL
peso molecular
calculated mol wt 129 kDa
embalagem
pkg of 100 μg
condição de armazenamento
avoid repeated freeze/thaw cycles
Impurezas
endotoxin, tested
nº de adesão UniProt
temperatura de armazenamento
−20°C
Informações sobre genes
human ... MET(4233)
Ações bioquímicas/fisiológicas
Heterodimeric transmembrane glycoprotein with binding capacity for c-Met. Activation of this receptor has been correlated with induction of the Ras pathway.
Outras notas
Extracellular domain of c-Met fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.
forma física
Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing 5 mg bovine serum albumin.
Nota de análise
The biological activity is measured by its ability to bind human HGF.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Yaroslava M Chalenko et al.
International journal of molecular sciences, 24(8) (2023-04-28)
Listeria monocytogenes virulence factor InlB specifically interacts with the receptors c-Met and gC1q-R. Both receptors are present in non-professional and professional phagocytes, including macrophages. Phylogenetically defined InlB isoforms differently support invasion into non-professional phagocytes. This work deals with the effects
M Park et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(18), 6379-6383 (1987-09-01)
We isolated overlapping cDNA clones corresponding to the major MET protooncogene transcript. The cDNA nucleotide sequence contained an open reading frame of 1408 amino acids with features characteristic of the tyrosine kinase family of growth factor receptors. These features include
Egor V Kalinin et al.
Drug development research, 82(1), 123-132 (2020-08-25)
Hepatocyte growth factor (HGF) is central to liver regeneration. The Internalin B (InlB) protein is a virulence factor produced by the pathogenic bacterium Listeria monocytogenes. InlB is known to mimic HGF activity by interacting with the HGF receptor (HGFR) and
Xin Li et al.
Frontiers in cell and developmental biology, 9, 661122-661122 (2021-05-04)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with minimally effective treatments, highlighting the importance of developing novel biomarkers and therapeutic targets. Here, we disclosed the mechanisms that leukocyte cell-derived chemotaxin-2 (LECT2) modulates PDAC development using in
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