This product is not considered lysine-fixable. The material would have to be chemically treated in order to be suitable. Typically, dextrans used to prepare lysine-fixable products are anionic (see product 90718). Should it be of interest, product B9139 is a Biotin-dextran, lysine-fixable product option. See the link below to review this product page:
https://www.sigmaaldrich.com/product/sigma/b9139
FD70S
Isotiocianato de fluoresceína–dextrana
average mol wt 60,000-76,000
Sinônimo(s):
FITC–Dextrana
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100 MG
R$ 683,00
250 MG
R$ 1.156,00
1 G
R$ 3.631,00
5 G
R$ 13.822,00
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Alterar visualização
100 MG
R$ 683,00
250 MG
R$ 1.156,00
1 G
R$ 3.631,00
5 G
R$ 13.822,00
About This Item
Produtos recomendados
fonte biológica
bacterial (Leuconostoc mesenteroides)
Nível de qualidade
conjugado
FITC conjugate
Formulário
powder
peso molecular
average mol wt 60,000-76,000
Extensão da rotulagem
0.003-0.020 mol FITC per mol glucose
cor
yellow to yellow-orange
solubilidade
H2O: 25 mg/mL, clear to slightly hazy, yellow-orange
temperatura de armazenamento
2-8°C
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Aplicação
Dextrana marcada com isotiocianato de fluoresceína para possível uso em estudos de perfusão em animais.
FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.[1] Small FITC-dextrans are also used to measure processes such as endocytosis and cell junction permeability.[2] FITC-dextran 70 kDa (FD-70) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. FD-70 may be used in microvascular and cell monolayer permeability studies.[3]
Ligação
Similar to FD-70, but produced by Sigma.
Outras notas
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Conteúdo relacionado
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.
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Is this dextran lysine-fixable?
1 answer-
Helpful?
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How long would a diluted stock (i.e. 5 mg/mL) be stable for at 4C?
1 answer-
The long term solution stability of this product has not been determined. Solutions should be protected from light. Per literature references, FITC-Dextran is stable in vivo for more than 24 hours. Please see the link below for additional information.
https://www.sigmaaldrich.com/technical-documents/technical-article/cell-culture-and-cell-culture-analysis/cell-based-assays/fluorescein-isothiocyanate-dextranHelpful?
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