Pular para o conteúdo
Merck
Todas as fotos(3)

Documentos

F0756

Sigma-Aldrich

Fusidic acid

Sinônimo(s):

Ramycin

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(3)

About This Item

Fórmula empírica (Notação de Hill):
C31H48O6
Número CAS:
6990-06-3
Peso molecular:
516.71
Número CE:
230-256-0
Número MDL:
MFCD00865135
Código UNSPSC:
12352106
ID de substância PubChem:
57654174
NACRES:
NA.77

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[H][C@@]12CC[C@@]3(C)[C@@]([H])([C@H](O)C[C@@]4([H])\C([C@H](C[C@]34C)OC(C)=O)=C(/CC\C=C(\C)C)C(O)=O)[C@@]1(C)CC[C@@H](O)[C@H]2C

InChI

1S/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20-/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-/m0/s1

chave InChI

IECPWNUMDGFDKC-MZJAQBGESA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Aplicação

Fusidic acid has been used:
  • as a standard in thin-layer chromatography (TLC)-densitometric method
  • to study its ability to bind to human serum albumin
  • as an antibiotic in combination with tannic acid to determine minimum inhibitory concentrations (MIC) in methicillin-resistant Staphylococcus aureus (MRSA)

Ações bioquímicas/fisiológicas

Fusidic acid is a tetracyclic triterpenoid with antibiotic activity against Gram-positive bacteria. It is derived from Fusidium coccineum. It shows its activity against anaerobes, corynebacterial, Nocardia, and Neisseria species. Fusidic acid exhibits therapeutic effects against Staphylococcal infections, skin infections.
Suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P264 - P270 - P301 + P312 + P330 - P501

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 8

1 of 8

Lithium mupirocin Supplement suitable for microbiology, Selectively inhibits the growth of lactic acid bacteria

Millipore

69732

Lithium mupirocin Supplement

propionato de clobetasol analytical standard

Supelco

C8037

propionato de clobetasol

Betamethasone ≥98%

Sigma-Aldrich

B7005

Betamethasone

Rifampicina ≥95% (HPLC), powder or crystals

Sigma-Aldrich

R3501

Rifampicina

Cephalexin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1848

Cephalexin

Clindamycin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1159

Clindamycin hydrochloride

Erythromycin potency: ≥850 μg per mg

Sigma-Aldrich

E6376

Erythromycin

Quercetin hydrate ≥95%

Sigma-Aldrich

337951

Quercetin hydrate

Jade Bojkovic et al.
Journal of bacteriology, 198(4), 731-741 (2015-12-17)
Lipid A on the Gram-negative outer membrane (OM) is synthesized in the cytoplasm by the Lpx pathway and translocated to the OM by the Lpt pathway. Some Acinetobacter baumannii strains can tolerate the complete loss of lipopolysaccharide (LPS) resulting from
Tannic acid as phytochemical potentiator for antibiotic resistance adaptation
Myint K, et al.
APCBEE procedia, 7, 175-181 (2013)
Silke Besier et al.
Molecular microbiology, 47(2), 463-469 (2003-01-10)
Fusidic acid is a potent antibiotic against severe Gram-positive infections that interferes with the function of elongation factor G (EF-G), thereby leading to the inhibition of bacterial protein synthesis. In this study, we demonstrate that fusidic acid resistance in Staphylococcus
R Di Marco et al.
Journal of autoimmunity, 13(2), 187-195 (1999-09-10)
The immunomodulating antibiotic drug fusidic acid and its sodium salt sodium fusidate (fusidin) ameliorate several organ-specific immunoinflammatory diseases. Because preliminary observations suggest that fusidin may also exert a beneficial effect in Guillain-Barré syndrome (GBS), here we have studied the effects
Christine Oswald et al.
Nature communications, 7, 13819-13819 (2016-12-17)
The deployment of multidrug efflux pumps is a powerful defence mechanism for Gram-negative bacterial cells when exposed to antimicrobial agents. The major multidrug efflux transport system in Escherichia coli, AcrAB-TolC, is a tripartite system using the proton-motive force as an
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica