D9500

2′-Deoxyguanosine 5′-monophosphate sodium salt hydrate

≥99% (HPLC)

• Sinônimo(s): 5′-Deoxyguanylic acid, dGMP
• Fórmula empírica (Notação de Hill): C₁₀H₁₄N₅O₇P · xNa⁺ · yH₂O
• Peso molecular: 347.22 (anhydrous free acid basis)
• Número MDL: MFCD00150780
• Código UNSPSC: 41106305
• ID de substância PubChem: 24894297
• NACRES: NA.51

Propriedades

• Ensaio: ≥99% (HPLC)
• Formulário: powder
• solubilidade: water: 50 mg/mL, clear, colorless
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O.[Na+].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP(O)([O-])=O)O3)C(=O)N1
• InChI: 1S/C10H14N5O7P.Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;1H2/q;+1;/p-1/t4-,5+,6+;;/m0../s1
• chave InChI: UVKXYXSKMTUDML-FVALZTRZSA-M

Descrição

Aplicação

2′-Deoxyguanosine 5′-monophosphate (dGMP) is used as a substrate of guanylate kinase(s) (EC 2.7.4.8) to form dGDP which upon phosphorylation to dGTP supports DNA biosynthesis. dGMP is use to study physiochemical characteristics of guanine based molecules.

2′-Deoxyguanosine 5′-monophosphate sodium salt hydrate has been used:

• in reversed-phase high pressure liquid chromatography (HPLC) analysis[1]
• to determine the effects of deoxy-mononucleotides on spontaneous proliferating CaCo-2 cell lines[2]
• to determine its capacity to stimulate immune cell growth and function and used influenza virus antigen as an immunostimulant in vitro[3]

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3